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Author

Zheng You

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Oct 2026

Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.

Cas13a enzymes are particularly attractive for nucleic acid detection due to their robust collateral activity. Recently, there has been a surge in the discovery and engineering of thermostable Cas13a proteins for nucleic acid detection. The thermostable Cas13a from Thermoclostridium caenicola (TccCas13a) was identified...

S. J. Oladeji, Diego H. Gonzalez, Xiang-Yu Deng et al. · 0 citations

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