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Author

Zhenyu Hou

2 papers indexed here

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Sep 2026

Manganese-doped zinc oxide Nano-agonists activating the cGAS-STING pathway to potentiate anti-tumor immunotherapy and reprogram the immunosuppressive tumor microenvironment.

The cyclic GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) innate immune pathway is an intriguing, but still challenging, target for cancer immunotherapy. The current small molecule STING agonists have several limitations, such as low membrane permeability, rapid enzymatic degradation, lack of tumor accu...

Zhen-Yu Hou, Hao-Lin Xu, Dong-Dong Zhou et al. · 0 citations
Jul 2026

Quercetin exerts radioprotective effects against radiation-induced intestinal injury with involvement of the PI3K-AKT/Caspase-3 axis

QUE protects against RIII by scavenging ROS and modulating apoptosis-related signaling, with evidence supporting the involvement of the PI3K-AKT/Caspase-3 axis, with the PI3K-AKT/Caspase-3 axis identified as central to these protective effects.

Qing Guo, Zhi-Bing Tang, Zhen-Yu Hou et al. · 0 citations

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