Although injectable anemoside B4 (AB4) has therapeutic potential for atopic dermatitis (AD), its clinical use is restricted by safety and pharmacokinetic issues. Therefore, we designed 42 AB4 derivatives, established a preliminary SAR for anti-inflammatory and antiallergic activities, and selected three promising compo...
Heng-Yi Li, Ye-Xin Du, Qiu-Rong Li et al.· Journal of Medicinal Chemist...· 0 citations
VisCAD is presented, a foundation model suite designed to provide both broad generalization and strong CAD capability for realistic industrial products that includes a domain-specific harness that leverages frontier models for complex assembly generation and demonstrates advantages over general-purpose harnesses in bot...
Guan-Ling Li, Zhi-Chao Huang, Hui-Mu Yu et al.· 0 citations
Results show that execution alone is insufficient to characterize realistic CAD modeling and that frontier models and agents differ substantially across executability, IoUs, and visual-semantic identity.
Guan-Ling Li, Zhi-Chao Huang, Hui-Mu Yu et al.· 0 citations
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