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Author

Zhi-Xun Guo

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3 papers indexed here

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Review Open access Aug 2026

Protective effects and mechanisms of puerarin in ovariectomized animal models of osteoporosis: a systematic review and meta-analysis of preclinical studies

Background Osteoporosis is a prevalent systemic metabolic disease, and osteoporotic fractures severely compromise patients’ health and quality of life. Postmenopausal osteoporosis is a major form of primary osteoporosis in women and is primarily attributable to estrogen deficiency. Ovariectomized animal models are wide...

Chao Dong, Zhi-Xun Guo, An Hu et al. · 0 citations
Sep 2026

A hypoxia-derived seven-gene signature reflects immune remodeling in diabetic kidney disease: integrated transcriptomic analysis and experimental validation.

This hypoxia-associated seven-gene signature showed diagnostic potential and reflected immune and molecular heterogeneity in DKD and was associated with macrophage- and neutrophil-related immune remodeling.

Yue Ji, Jia-Kun Zhang, Xi Guo et al. · 0 citations
#protein folding Review Open access Aug 2026

Endoplasmic reticulum stress in Hashimoto’s thyroiditis: a candidate amplification node linking thyroid-specific vulnerability and immune dysregulation

A testable positive-feedback perspective in which thyrocyte ERS injury and immune effector amplification may mutually reinforce one another is proposed, in which thyrocyte ERS injury and immune effector amplification may mutually reinforce one another.

X. Si, Zhi-Xun Guo, Ge-Na Jiao et al. · 0 citations

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