Author

Zi-Wen Wang

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Review Open access Sep 2026

Chimeric antigen receptor (CAR)-T cell therapy for solid tumors in pediatric patients: current breakthroughs, dilemmas, and strategies

Recent advances, persistent challenges, and emerging strategies for CAR-T cell therapy in pediatric solid tumors are summarized and rational combination strategies involving CAR-T cell therapy with chemotherapy, radiotherapy, and immune checkpoint inhibitors aimed at improving therapeutic efficacy and safety are discus...

Yu-Miao Mai, Zi-Wen Wang, Juan Wang et al. · Experimental Hematology & On... · 0 citations

#protein folding Open access Sep 2026

Structural and Biochemical Analysis of Human Schlafen5 Reveals the Molecular Basis of Its Anti-Tumor Function

Background: Schlafen5 (SLFN5) is an IFN-inducible member of the SLFN protein family involved in immune regulation, viral inhibition and tumor control. Recently, SLFN5 was suggested to inhibit the invasion of many kinds of malignant cells, and its expression positively correlates with the overall survival of relevant pa...

Jun-Ying Ou, Jin-Yu Yang, Meng-Ni Luo et al. · Health and Metabolism · 0 citations