Background Parkinson’s disease (PD) is characterized by the progressive loss of midbrain dopaminergic (DA) neurons and aberrant α-synuclein (α-syn) aggregation, yet disease-modifying therapies that simultaneously retard neurodegeneration and foster regeneration remain lacking. Methods In this study, we isolated extrace...
Zhen Qi, Xiao-Wen Li, Xiao Jin et al.· bioRxiv· 0 citations
This article adopts a multi-dimensional integration perspective to systematically summarize innovative breakthroughs in the construction of cardiac organoids through intelligent biomanufacturing, neuro-vascular-immune co-construction, and single-cell omics.
Current evidence on the roles of EVs in key pathological processes of HF, including inflammation, mitochondrial dysfunction, myocardial hypertrophy, fibrosis, apoptosis, and angiogenesis are summarized and their potential as circulating biomarkers for the diagnosis and prognosis are discussed.
Tingting Li, Jin Yang, Xin-Yue Ding et al.· Frontiers in Pharmacology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
