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human-computer interaction

495 papers

#artificial intelligence Conference Open access May 2026

UIC-AIHealth4All at ArchEHR-QA 2026: Answer-First Evidence Grounding for Clinical Question Answering

The UIC-AIHealth4All system for ArchEHR-QA 2026, a shared task on grounded question answering from electronic health records, is described and an answer-first pipeline in which the model generates candidate answers citing specific note sentences is proposed, exploiting the asymmetry between judging relevance in the abstract versus relative to a generated answer.

Mohammad Arvan, Hossein Haeri, Natalie Parde et al. · 0 citations
#artificial intelligence Preprint Aug 2026

CrabOS: An Operating System for Human-AI Co-inhabitation

CrabOS elevates support for complex tasks with alternating human and AI leadership from bridge-dependent application-level solutions to native operating-system capabilities, which provide a new foundation for developing and running AI agents.

Qi Yang, Yun Ma · 0 citations
#artificial intelligence Preprint Aug 2026

Generative AI Expands the Intellectual Reach of Course Based Undergraduate Research Experiences (CUREs)

Course-based undergraduate research experiences (CUREs) broaden access to authentic scientific inquiry through responsive instructor support as research problems become increasingly complex. Generative artificial intelligence (GenAI) may extend this support by providing individualized assistance that can adapt as student needs change. However, how embedding GenAI within a CURE to provide support across the research process impacts student inquiry, collaboration, and scientific reasoning remains unresolved. Here we use longitudinal qualitative data collected across three semesters of a bioinformatics and genomics CURE to show that GenAI expanded the intellectual reach of the research experience in three distinct ways. First, personalized, on-demand scaffolding allowed students to move beyond the boundaries of instructor expertise and transform their own interests into researchable inquiry, with all teams developing distinct self-directed projects rather than selecting instructor-provided topics. Second, GenAI became part of the distributed cognitive system of research teams, helping novice researchers communicate and coordinate across differentiated expertise without eliminating specialization. Third, expanded capability did not replace the need for disciplinary judgment. Students increasingly validated, revised, or rejected AI-generated contributions, such that research independence emerged through retained intellectual responsibility. Together, these findings suggest that GenAI can extend the reach of CUREs by expanding what novice researchers can investigate, how they can collaborate, and the level of responsibility they can assume while preserving human judgment central to authentic scientific inquiry.

Aditi Babar, K. Davin, A. Dornburg · 0 citations
#artificial intelligence Preprint Jul 2026

Not All Explanations Are Sought: Information-Seeking Psychology for Human-Centered XAI

This position paper argues that human-centered explainable AI (HCXAI) should incorporate insights from the psychology of information seeking. Drawing on Sharot and Sunstein's framework of information-seeking motives, we propose that people evaluate whether to engage with explanations based on three types of expected utility: instrumental (will it help me act better?), hedonic (will it make me feel better?), and cognitive (will it improve my understanding?). Each utility is estimated through a lens shaped by well-documented cognitive biases, including illusion of control, automation bias, unrealistic optimism, impact bias, overconfidence, and confirmation bias. These biases can lead to two failure modes: excessive information-seeking that fragments attention without improving decisions, and insufficient information-seeking that leaves critical risks and misunderstandings unexamined. This challenge is particularly acute for agentic AI systems, where explanations must support not just understanding a single output but anticipating cascading actions, assessing risks, and deciding when to intervene. By integrating information-seeking psychology into HCXAI, we advocate for a shift from making explanations available to making them sought: designing systems that account for when and why users actually want to know.

Andrea Beretta, Salvatore Rinzivillo · 0 citations
#computer vision Preprint Aug 2026

Trustworthy RAG: An Evaluation Agent for Detecting Misinformation and Knowledge Poisoning in Generative AI Systems

An Evaluation Agent, middleware that combines Natural Language Inference factual verification, a five-signal poison detector with relevance-weighted aggregation, and a Trust Index is proposed, which reliably blocks instruction injection of unsafe advice while contradiction and subtle semantic weakening remain hard.

Balkrishna Giri, M. Hasan, Jussi Rasku et al. · 0 citations
#human-computer interacti... Preprint Aug 2026

Poetic Heritage for Culturally Grounded Emotional Support: An Interaction Design Framework and Its Multimodal Agentic Instantiation

The work shows how generative AI can mediate engagement with poetic heritage in culturally grounded emotional-support interactions and suggests that culturally grounded content and structured guidance should anchor system design, while multimodal presentation may strengthen resonance and engagement.

Yang-Ming Zhang, Zhi-Qian Li, Bin Wu et al. · 0 citations

ProphDR: An Interpretable Deep Learning Model for Predicting Cancer Drug Response via Multi-Omics and Cross-Attention Mechanisms.

ProphDR is an interpretable deep learning framework that integrates multiomics data and drug structural information using a hierarchical attention mechanism, and generates biologically interpretable attention maps that highlight key pharmacophores and resistance-related genes consistent with established mechanisms in NSCLC and BRCA.

Yundian Zeng, Qing Ye, Jike Wang et al. · 0 citations
#computer vision Preprint Aug 2026

CodeAssay: A Multi-Metric Benchmark with Audited Ground Truth for LLM Code Generation

These findings show that reliable evaluation of LLM-generated code requires validated ground truth, protected tests, and multiple explicitly interpreted measures, and that CodeAssay provides a reproducible basis for evidence-based model evaluation in AI-augmented software development.

Shahbaz Siddeeq, Muhammad Waseem, Umar Subhan Malhi et al. · 0 citations
#machine learning Open access Jun 2026

Unified heterogeneity-aware benchmark of drug synergy prediction: a cross-study analysis of traditional machine learning and graph deep learning models.

The first comprehensive benchmarking framework specifically designed to accommodate inter-dataset heterogeneity is presented, finding that well-designed small datasets can match or even surpass the performance of larger benchmarks, suggesting that different metrics are applicable to different datasets/testing scenarios.

Yingjuan Cheng, Qing Ye, Linlong Jiang et al. · 0 citations

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