Recovering the 9D pose of objects, both their 6D pose and 3D dimensions, under clutter and occlusion is a core requirement for warehouse automation, logistics, and manufacturing. Model-based methods are accurate but assume an instance-specific CAD model for every object, which is costly to maintain as inventories change. Model-free and category-level methods relax this assumption, yet they remain vulnerable to the symmetry, weak texture, and heavy occlusion that characterize stacked storage boxes, and they ignore the strong structural priors such scenes provide. We present \textbf{AnyBox}, an efficient zero-shot framework that exploits the geometric regularity of boxes to jointly recover pose and dimensions from a single RGB-D observation. Starting from a canonical category template, AnyBox alternates between pose and scale estimation, using the discrepancy between the reprojected template and the observed mask to drive a binary search over box dimensions. Two lightweight components make this practical: a depth-consistency filter that rejects the implausible hypotheses induced by box symmetry, and an early-stopping rule that replaces the remaining search with a single closed-form update. On public benchmarks and an in-house warehouse dataset, AnyBox improves detection AP by up to 36 points, more than doubling the previous best, and approaches instance-level pipelines that have access to ground-truth CAD models. These gains transfer downstream, raising success by 28\% on a cluttered robotic box-shelving task.
Yintao Ma, Sajjad Pakdamansavoji, Charles Eret et al.· 0 citations
The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice. This has catalyzed a shift from single-step answer generation to the development of LLMs explicitly designed for medical reasoning. This paper provides the first systematic review of this emerging field. We propose a taxonomy of reasoning enhancement techniques, categorized into training-time strategies (e.g., supervised fine-tuning, reinforcement learning) and test-time mechanisms (e.g., prompt engineering, multi-agent systems). We analyze how these techniques are applied across different data modalities (text, image, code) and in key clinical applications such as diagnosis, education, and treatment planning. Furthermore, we survey the evolution of evaluation benchmarks from simple accuracy metrics to sophisticated assessments of reasoning quality and visual interpretability. Based on an analysis of 60 seminal studies from 2022-2025, we conclude by identifying critical challenges, including the faithfulness-plausibility gap and the need for native multimodal reasoning, and outlining future directions toward building efficient, robust, and sociotechnically responsible medical AI.
Zizhan Ma, Wenxuan Wang, Meidan Ding et al.· 0 citations
Synthetic data generation is increasingly used in machine learning for training and data augmentation. Yet, current strategies often rely on external foundation models or datasets, whose usage is restricted in many scenarios due to policy or legal constraints. We propose ScoreMix, a self-contained synthetic generation method to produce hard synthetic samples for recognition tasks by leveraging the score compositionality of diffusion models. The approach mixes class-conditioned scores along reverse diffusion trajectories, yielding domain-specific data augmentation without external resources. We systematically study class-selection strategies and find that mixing classes distant in the discriminator's embedding space yields larger gains, providing up to 3% additional average improvement, compared to selection based on proximity. Interestingly, we observe that condition and embedding spaces are largely uncorrelated under standard alignment metrics, and the generator's condition space has a negligible effect on downstream performance. Across 8 public face recognition benchmarks, ScoreMix improves accuracy by up to 7 percentage points, without hyperparameter search, highlighting both robustness and practicality. Our method provides a simple yet effective way to maximize discriminator performance using only the available dataset, without reliance on third-party resources. Paper website: https://parsa-ra.github.io/scoremix/.
Existing LLM-based agents have achieved strong performance on held-in tasks, but their generalizability to unseen tasks remains poor. Hence, some recent work focus on fine-tuning the policy model with more diverse tasks to improve the generalizability. In this work, we find that finetuning a reward model to guide the policy model is more robust than directly finetuning the policy model. Based on this finding, we propose AgentRM, a generalizable reward model, to guide the policy model for effective test-time search. We comprehensively investigate three approaches to construct the reward model, including explicit reward modeling, implicit reward modeling and LLM-as-a-judge. We then use AgentRM to guide the answer generation with Best-of-N sampling and step-level beam search. On four types of nine agent tasks, AgentRM enhances the base policy model by $8.8$ points on average, surpassing the top general agent by $4.0$. Moreover, it demonstrates weak-to-strong generalization, yielding greater improvement of $12.6$ on LLaMA-3-70B policy model. As for the specializability, AgentRM can also boost a finetuned policy model and outperform the top specialized agent by $11.4$ on three held-in tasks. Further analysis verifies its effectiveness in test-time scaling. Codes will be released to facilitate the research in this area.
Yu Xia, Jingru Fan, Weize Chen et al.· 0 citations
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Composing independently trained LoRA adapters into a single large language model is useful for multi-domain adaptation, especially when the original training data cannot be shared. A common approach is to use MoE-style routing over LoRA experts, but for frozen pretrained adapters, soft weighted combinations can change the unit-scale additive update under which each LoRA module was originally trained. We propose \textbf{Hard-Routed MoR-LoRA}, a two-stage framework for composing frozen reasoning LoRA experts through unit-scale hard selection. First, domain-specific LoRA adapters are trained independently using reinforcement learning from verifiable feedback to obtain reasoning experts. Then, all experts are frozen, reasoning traces are distilled from them, and only a lightweight shared router together with a small attention LoRA is trained for integration. The router selects exactly one expert per token using hard top-1 routing, while a straight-through estimator enables gradient-based training. Experiments across five benchmarks, multiple model scales, and additional model families show that Hard-Routed MoR-LoRA preserves expert behavior while requiring substantially fewer trainable parameters than soft-routing mixture baselines. Our analysis further shows that normalized soft mixtures often concentrate most routing mass on a single expert, suggesting that hard unit-scale routing provides a simple and efficient abstraction for frozen LoRA expert composition.
Seyed Alireza Molavi, Zhan Su, Yan Hu et al.· 0 citations
Agent Skills today consist largely of free-form prose requiring the agent to read, interpret, and re-derive how to act in every session. This imposes two compounding costs: reduced reliability on implementation-heavy tasks, and difficulty in skill creation and improvement, since editing prose is a fragile process that both humans and agents struggle with, particularly for domain-specific procedural knowledge underrepresented in model training. The Agent Instruction Protocol (AIP) addresses both by modeling a skill as a directed execution graph: discrete steps as nodes backed by deterministic scripts or natural-language descriptions, connected by explicit typed input/output edges, and governed by a schema-validated YAML specification. A compiler meta-skill translates existing human-written skills into this form. The benefits are twofold. First, compiling human-written skills to AIP raised Claude Sonnet's mean task reward from 0.60 to 0.71 and pass rate from 53% to 67% across 27 real agent tasks from SkillsBench - a statistically significant gain (Wilcoxon signed-rank p = 0.011), winning 12 tasks to 2 with 13 ties - often in less wall-clock time. The graph delivers vetted, runnable units to the agent rather than asking it to re-derive code, commands, and tool calls from natural language. Second, on creation and improvement, because each skill is schema-validated, functionally testable, and addressable node-by-node, failures can be diagnosed and repaired precisely. Two authored-skill failures were traced to the script level. After adjusting the AIP spec and recompiling, both recovered with zero regressions (one task going from 0/5 to 5/5), turning skill improvement into a measurable tuning loop rather than a prose rewrite. That same graph structure supports corpus-level governance and skill introspection, and provides a natural action space for reinforcement learning over skills.
Extreme weather and volatile wholesale electricity markets expose residential consumers to catastrophic financial risks, yet demand response at the distribution level remains an underutilized tool for grid flexibility and energy affordability. While a demand-response program can shield consumers by issuing financial credits during high-price periods, optimizing this sequential decision-making process presents a unique challenge for reinforcement learning despite the plentiful offline historical smart meter and wholesale pricing data available publicly. Offline historical data fails to capture the dynamic, interactive feedback loop between an electric utility's pricing signals and customer acceptance and adaptation to a demand-response program. To address this, we introduce DR-Gym, an open-source, online Gymnasium-compatible environment designed to train and evaluate demand-response from the electric utility's perspective. Unlike existing device-level energy simulators, our environment focuses on the market-level electric utility setting and provides a rich observational space relevant to the electric utility. The simulator additionally features a regime-switching wholesale price model calibrated to real-world extreme events, alongside physics-based building demand profiles. For our learning signal, we use a configurable, multi-objective reward function for specifying diverse learning objectives. We demonstrate through baseline strategies and data snapshots the capability of our simulator to create realistic and learnable environments.
Jose E. Aguilar Escamilla, Lingdong Zhou, Xiangqi Zhu et al.· 0 citations
Recent Artificial Intelligence (AI) models have matched or exceeded human experts in several benchmarks of biomedical task performance, but surgical benchmarks in particular are often missing from prominent medical benchmark suites. Since surgery requires integrating disparate tasks, generally-capable AI models could be particularly attractive as a collaborative tool if performance could be improved. On the one hand, the canonical approach of scaling architecture size and training data is attractive, especially since there are millions of hours of surgical video data generated per year. On the other hand, preparing surgical data for AI training requires significantly higher levels of professional expertise, and training on that data requires expensive computational resources. These trade-offs paint an uncertain picture of whether and to-what-extent modern AI could aid surgical practice. In this paper, we explore this question through a case study of surgical tool detection using state-of-the-art AI methods available in 2026. We demonstrate that even with multi-billion parameter models and extensive training, current Vision Language Models fall short in the seemingly simple task of tool detection in neurosurgery. Additionally, we show scaling experiments indicating that increasing model size and training time only leads to diminishing improvements in relevant performance metrics. Thus, our experiments suggest that current models could still face significant obstacles in surgical use cases. Moreover, some obstacles cannot be simply ``scaled away'' with additional compute and persist across diverse model architectures, raising the question of whether data and label availability are the only limiting factors. We discuss the main contributors to these constraints and advance potential solutions.
Kirill Skobelev, Eric Fithian, Yegor Baranovski et al.· 0 citations
Affective computing has matured rapidly in laboratory settings, yet no prior dataset combines (i) months-to-years of duration, (ii) a naturalistic workplace context, (iii) a stable small-team social structure, and (iv) a fully passive sensing protocol that survives institutional review. We introduce WELD, the first dataset to satisfy all four. WELD comprises 733,780 per-frame seven-class facial-expression probability vectors from 49 employees of a Chinese software company over 30.1 months (Nov 2021 - May 2024) -- the longest naturalistic in-the-wild emotion corpus and the only multi-year corpus supporting both within-individual longitudinal and within-team relational analyses on the same subjects. Data are released under a four-tier access model with only aggregated probabilities publicly downloadable. We validate the corpus by replicating three established phenomena (+43.1% weekend valence boost; 13:00-trough diurnal cycle; Shanghai 2022 lockdown effect d=-0.40), and report four novel findings: (1) variance decomposition attributes 19.3% of daily-valence variance to between-person differences and 29.8% to month seasonality -- a quantitative ceiling for future predictive models; (2) Hidden Markov decomposition reveals six emotional regimes with asymmetric negative-state dwell times (16-18 d vs 3 d); (3) leave-one-person-out turnover prediction reaches AUC=0.79 yet a Cox concordance index of only 0.52, exposing a metric-trap when AUC is reported without survival-aware baselines; (4) the corpus reveals systematic over-prediction of "angry" by an off-the-shelf FER model on neutral Asian faces (0.194 vs ~0.05 Western priors), making WELD valuable for FER fairness audits. A complex-systems analysis of the corpus appears as a companion preprint (arXiv:2510.16046).
Large Language Models (LLMs) struggle with reliably generating highly structured outputs, such as program code, mathematical formulas, or well-formed markup. Constrained decoding approaches mitigate this problem by greedily restricting what tokens an LLM can output at each step to guarantee that the output matches a given constraint. Specifically, in grammar-constrained decoding (GCD), the LLM's output must follow a given grammar. In this paper, we demonstrate that GCD techniques (and in general constrained decoding techniques) can distort the LLM's distribution, leading to outputs that are grammatical but appear with likelihoods that are not proportional to the ones given by the LLM, and so ultimately are low-quality. We call the problem of aligning sampling with a grammar constraint, grammar-aligned decoding (GAD), and propose adaptive sampling with approximate expected futures (ASAp), a decoding algorithm that guarantees the output to be grammatical while provably producing outputs that match the conditional probability of the LLM's distribution conditioned on the given grammar constraint. Our algorithm uses prior sample outputs to soundly overapproximate the future grammaticality of different output prefixes. Our evaluation on code generation and structured NLP tasks shows how ASAp often produces outputs with higher likelihood (according to the LLM's distribution) than existing GCD techniques, while still enforcing the desired grammatical constraints.
Kanghee Park, Jiayu Wang, Taylor Berg-Kirkpatrick et al.· 0 citations
Many recurring text functions are easy to describe but difficult to implement with rules, while calling a large remote model for every input introduces repeated cost, latency, and dependency on a provider. We present compile by training, which turns a natural-language specification into a reusable neural function. At compile time, teacher models generate task-specific examples that are used to train a small adapter for a compact interpreter. The resulting function runs without the teachers and can be stored, versioned, and composed like ordinary software. On FuzzyBench-Hard, a subset on which the Program-as-Weights fast compiler produced no exact matches, compile by training reaches 83.6% semantic accuracy. This higher accuracy comes with a higher compile-time cost: roughly a minute rather than seconds for the fast compiler. We deploy the compiler in a public interactive service and demonstrate compiled functions in a multi-site website helper, a language-controlled 3D avatar, and a bidirectional English-Claudish translator.
Yuntian Deng, Pengyu Nie, Stuart Shieber· 0 citations
This paper presents a low-cost, open experimental platform for research in end-to-end autonomous driving with miniature Ackermann vehicles. The platform combines a physical vehicle, a printed urban track, data collection tools, trajectory registration, and a Webots digital twin, enabling controlled experiments that connect simulation-based autonomous-driving methods to real-world execution. As a first baseline, we implement command-conditioned behavior cloning, in which a neural policy receives an on-board camera image and a high-level navigation command and outputs steering and speed. The system is evaluated both on the physical vehicle and in simulation. In real closed-loop experiments, the learned policy follows lanes and executes commanded turns, reaching a mean cross-track error of 6.1 cm with respect to the reference route, close to the 4.7 cm observed in human demonstrations. In the digital twin, camera field of view has a strong effect on performance, reducing the mean cross-track error from 35.6 to 3.3 cm when widened from 58 to 120 degrees. Using the digital twin to generate synthetic driving data and a learned sim-to-real image translator to reduce the appearance gap, we further show that a higher-capacity policy trained on this synthetic data combined with real demonstrations is the only configuration that completes all four track routes in closed loop, whereas the compact baseline and the same network trained on real data alone complete fewer. These results establish the open platform as a practical testbed for sim-to-real studies and provide an initial command-conditioned imitation-learning baseline; we release it to support reproducible research.
Gustavo Claudio Karl Couto, Eric Aislan Antonelo, Gabriel George Zipperer· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
MIT News · Artificial Intelligence· news.mit.eduAug 24, 2026
A new method for surgically removing training examples from a model reveals that as datasets grow, the link between what a model learns and what it produces dissolves.
