Nanoliposomal curcumin protects against D-galactose-induced hepatic aging by targeting oxidative stress, mitochondrial dysfunction, and inflammatory signaling.

Liposomal Nano-Curcumin Attenuates Cisplatin-Induced Hepatotoxicity in Rats with Concomitant Regulation of Wnt/β-Catenin/GSK-3β and Nrf2 Signaling

N-Cur mitigates oxidative damage and inflammation, thereby preserving hepatic function during CDDP-based chemotherapy, and demonstrates significant potential as a hepatoprotective agent when administered concomitantly with CDDP chemotherapy.

Nanoliposomal silymarin as a multi-mechanistic therapy for NAFLD: dose-dependent amelioration of hepatic steatosis, fibrosis, and oxidative stress in a rat model

Liposomal Morin Attenuates DMH-Associated Colonic Oxidative Stress, Inflammation, and Apoptosis/Autophagy-Related Dysregulation in Rats

Background/Objectives: Oxidative stress, chronic inflammation, disrupted apoptosis, and altered autophagy are biological processes implicated in colorectal tumor development. Morin is a plant-derived flavonoid with antioxidant and anti-inflammatory properties, but its limited solubility and bioavailability may limit it...

Hypophyllanthin Protects Against Alcohol-Induced Hepatotoxicity in Rats: Involvement of Oxidative Stress, Inflammatory Cytokines, Apoptosis, and Autophagy

Introduction Ethanol consumption is a primary global health concern, frequently leading to severe hepatic injury. The present study assessed the hepatoprotective effects of hypophyllanthin against ethanol-induced hepatotoxicity in rats. Methods A Wistar rats were randomly assigned into five groups (n=6/group): Group I...

Protective Effects of Esculetin at two Different Doses on Oxidative Stress, Inflammation, and Fibrotic Changes in AlCl₃-Induced Cardiotoxicity in Rats

AlCl₃ exposure led to increased MDA levels and decreased GSH levels, with reduced SOD and CAT activities in heart tissue, which led to increased MDA levels and decreased GSH levels, with reduced SOD and CAT activities in heart tissue.

MOLECULAR EFFECTS OF QUINOA ON RAT KIDNEY: A DOSE-DEPENDENT STUDY ON PYROPTOSIS AND ANTIOXIDANT DEFENSE

Evidence is provided that dietary quinoa beneficially modulates renal molecular pathways involved in oxidative stress and inflammatory responses under physiological conditions.