Deciphering the role of histidine in cancer

Special Issue “Molecular Biomarkers in Cancers: Advances and Challenges”

Cancer remains one of the most formidable challenges in contemporary medicine, due to not only its substantial and growing global burden but also the profound biological heterogeneity that characterizes individual tumors [...].

Correction: Integrative subtyping by bile acid metabolism identifies CLCA1/UGT2A3/ZG16 as markers of immune dysfunction and poor prognosis in colorectal cancer

[This corrects the article DOI: 10.3389/fonc.2025.1739534.].

Lifelong Genetic Inhibition of PCSK9 and Hepatic Safety

This genetic association study investigates whether the full spectrum of rare PCSK9 loss-of-function variants is associated with incident liver-related outcomes, given the development of therapies targeting proprotein convertase subtilisin/kexin type 9 (PCSK9).

In Silico Assessment of Human Beta-Glucuronidase (GUSB) Expression and Prognostic Outcomes in Breast Cancer: Evaluating Tumor-Intrinsic and Microbial Perspectives

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Startups mine ‘dark proteome’ for new drug targets

A multimodal murmuration for immunotherapy