Aug 2026· Genes & Genomics· 0 citations· 29 references
Medicine
TL;DR
Findings support hsa-miR-200a as a potential breast cancer-associated miRNA biomarker candidate and highlight the utility of integrative transcriptomic and exploratory clinical serum approaches for future precision diagnostics.
The miR-6838-5p/miR-195-5p combination represents a promising circulating miRNA signature for invasive ductal breast carcinoma and its consistent discriminatory performance in the discovery cohort and an independent serum cohort supports further evaluation in larger prospective studies.
Mustafa Barış Zeytunlu, Fazilet Esra Incedere Duzdag, Hüseyin Esin et al.· Molecular Biology Reports· 0 citations
Circulating miR-141-3p shows promise as a non-invasive biomarker for BC detection and risk discrimination, although its specificity as a stand-alone marker may be limited.
T. T. Duong, Thanh Thi Ngoc Nguyen, L. H. Huynh et al.· Asian Pacific Journal of Can...· 0 citations
microRNAs (miRNAs) are emerging as promising biomarkers in hematological malignancies due to their stability in blood. This study aimed to investigate the differential expression of miRNAs in chronic myeloid leukemia (CML) and evaluate the potential of miR-451a as a candidate whole-blood miRNA marker.
We c...
Surbhi Gupta, Nitu Nigam, Abdullah H. Maad et al.· BMC Cancer· 0 citations
Background Ovarian cancer (OVCA) remains one of the most lethal gynecological malignancies, primarily due to late-stage diagnosis and the lack of reliable early-detection biomarkers. Circulating microRNAs (miRNAs) have emerged as promising non-invasive biomarkers for cancer detection and prognosis. Objective This study...
Ahmed El Hosseiny, Meriem Yagoubi, Ahmed Moustafa et al.· Frontiers in Genetics· 0 citations
Background/Objectives: Preoperative discrimination of benign from malignant adnexal masses remains a major clinical challenge, and circulating microRNAs (miRNAs) are candidate non-invasive biomarkers. This exploratory, hypothesis-generating study—not a diagnostic validation study—evaluated serum hsa-miR-200c-3p as a ca...
J. D. Santotoribio, Juan Corral-Pérez, Laura Ávila-Cabeza-de-Vaca et al.· Diagnostics· 0 citations
It is demonstrated that serum exosomal miR-17-3p is a promising biomarker for GC diagnosis and evaluation and validated candidate miRNAs using quantitative real-time PCR.
Jian-Ming Wei, P. Luo, W.-Q. Yao et al.· American Journal of Cancer R...· 0 citations
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