Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) Medication Titration Practices in Hemodialysis Patients in the US

Combining dietary fiber inulin with parathyroid hormone-lowering therapy improves bone remodeling and mechanics in a rat model of Chronic Kidney Disease-Mineral Bone Disorder.

INTRODUCTION Chronic kidney disease (CKD) has devastating effects on the skeletal system resulting in an increased fracture risk. CKD results in the buildup of metabolites in the blood (often referred to as uremic toxins), and several uremic toxins have been linked to adverse skeletal outcomes. We have shown that dieta...

Prevalence of Bone Mineral Disorders in Hemodialysis Patients: A Prospective Observational Study from a Tertiary Care Hospital in South India

Routine biochemical and BMD surveillance, with a particular focus on phosphate control, is warranted in this high-risk population of hemodialysis patients.

Neighborhood Socioeconomic Status, Bone and Vitamin D Nutritional Status markers in the Chronic Kidney Disease in Children Cohort

Chronic Kidney Disease-Mineral Bone Disorder (CKD-MBD) contributes to significant morbidity in children with CKD, including poor growth and increased cardiovascular risk. Prior research demonstrates the role of socioeconomic status (SES) in the levels of CKD-MBD markers within a pediatric dialysis population. Lit...

A Cross-Sectional Study on Detection of Chronic Kidney Disease and Bone Mineral Density Status in At-Risk Patients

Background: Chronic kidney disease (CKD) is commonly attributed to diabetes and hypertension and induces bone mineral density (BMD) losses, resulting in health implications. Objective: To detect CKD in patients with diabetes and/or hypertension and to evaluate their BMD of the lumbar spine and femoral regions, and tota...

Effects of Dialysate Calcium Concentration on Bone, Mineral Metabolism, and Vascular Outcomes in Maintenance Hemodialysis: A Systematic Review and Meta-Analysis

Background/Objectives: The optimal dialysate calcium concentration in maintenance hemodialysis remains uncertain because reducing calcium exposure may limit calcium loading but can also stimulate parathyroid hormone secretion and impair intradialytic cardiovascular stability. We evaluated randomized evidence across bon...

Phosphate storm in chronic kidney disease-mineral and bone disorder: practical clinical strategies for vascular calcification control.