Jul 2026· Biological Trace Element Research· 0 citations· 22 references
Medicine
TL;DR
Higher ZCR is consistently associated with hypertension across analytical approaches and subgroups, with a suggestive but not statistically significant pattern of effect modification by environmental metal exposure, support ZCR as a potentially informative indicator of essential metal imbalance relevant to blood pressure.
Insulin resistance might be a crucial mediated pathway between Se and outcomes and three multi-pollutant models revealed positive associations between metal mixtures and SUA as well as HUA, with Se being the primary contributor.
Jing-Fu Lai, Ya-Qin Zhang, Yun-Ting Zhang et al.· Frontiers in Public Health· 0 citations
Findings highlight the toxicological relevance of metal mixtures in cardiovascular disease and underscore the need for mechanistic studies to establish causality.
Introduction: Hypertension is a major public health challenge worldwide. In low- and middle-income countries, hypertension is rapidly increasing and contributes substantially to premature mortality. It is commonly associated with overweight and obesity. Growing evidence also indicates that environmental pollutants, par...
B. Dama, Karell Tchokonte Happi, Taty Brandy Perkwang et al.· Journal of Food Technology &...· 0 citations
Cadmium is a cumulative nephrotoxicant that injures the proximal tubule through oxidative stress and disrupted metal handling. Whether contemporary low-level exposure associates with albuminuria, and how those internal concentrations compare with in vitro bioactivity, remains incompletely defined. In NHANES 2011-2018 a...
January G. Msemakweli, Hussein Mohamed, Fabrice T. Nyambod et al.· Toxicology and Applied Pharm...· 0 citations
Low-density lipoprotein cholesterol and neutrophil-to-lymphocyte ratio were co-primary outcomes; systemic immune–inflammation index (SII) was secondary; Adjusted models used multiple imputation and false-discovery-rate (FDR) correction.
C. Buonerba, P. Montuori, E. Esposito et al.· Toxics· 1 citation
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