Comparative Visual Outcomes of Toric and Nontoric Intraocular Lenses Featuring Combined Diffractive Extended Depth of Focus and Multifocal Designs

Visual performance of a non-diffractive extended depth of focus IOL in stable early-stage Keratoconus: prospective pilot study

To evaluate visual performance, contrast sensitivity (CS), optical quality, and subjective satisfaction of Vivity extended depth-of-focus (EDOF) premium intraocular lens (pIOL) in early keratoconus (KC). In this prospective, interventional, single-center clinical study, ten patients with mild bilateral KC and cataract received AcrySof IQ Vivity pIOL. Pre- and postoperative assessments included monocular and binocular uncorrected and distance-corrected visual acuities at 4 m (UDVA, DCVA), uncorrected and distance-corrected intermediate and near visual acuities at 66 cm (UI66VA, DCI66VA) and 40 cm (UNVA, DCNVA), defocus curve, CS, wavefront aberrometry (RMS, PSF, Strehl ratio), halometry, and subjective outcomes. At 3 months, mean ± SD monocular DCVA in the dominant eyes (primary endpoint) was 0.06 ± 0.13 logMAR. A statistically significant improvement was observed between preoperative and postoperative monocular and binocular UDVA, UNVA, DCNVA (p < 0.001), and DCVA (p = 0.03). Binocular DCI66VA and UI66VA were 0.10 ± 0.15 and 0.14 ± 0.16 logMAR, respectively. The defocus curve was ≤ 0.20 logMAR from + 0.50 D to – 2.00 D. CS peaked under scotopic conditions at 6 cpd, total ocular RMS improved from 2.15 ± 1.98 to 1.09 ± 0.77 (p = 0.09). NEI-RQL-42 scores indicated favourable patient-reported outcomes, particularly for glare, clarity of vision, and satisfaction with correction. In this small prospective pilot study, bilateral implantation of a non-diffractive EDOF IOL was associated with favourable short-term visual outcomes in highly selected patients with stable early keratoconus. These preliminary findings suggest that early stable KC may not represent an absolute contraindication to non-diffractive EDOF IOL implantation, but larger comparative studies with longer follow-up are required.

Clinical outcomes of combined presbyopia and astigmatism correction following hydrophilic trifocal toric intraocular lens implantation in cataract patients: a prospective clinical study

A clearer understanding of the Liberty 677MTY trifocal toric IOL’s performance is offered, supporting its use as a safe and effective solution for achieving spectacle independence and enhancing postoperative quality of life.

Clinical Performance of an Isofocal Toric Intraocular Lens with Double C-Loop Haptics: A Multicenter Retrospective Study

Purpose To evaluate clinical outcomes in eyes with pre-existing astigmatism undergoing cataract surgery or refractive lens exchange with the implantation of an isofocal optic-design toric intraocular lens (IOL) with double C-loop haptics. Method This multicenter retrospective study comprised 100 eyes (65 patients) implanted with the Isopure Serenity toric IOL (BVI, Inc.) conducted across four sites. Postoperative evaluation at between 2 and 3 months included manifest refraction, monocular uncorrected and distance corrected visual acuity (UDVA and CDVA), monocular uncorrected and distance corrected intermediate visual acuity (UIVA and DCIVA, at 80 and 66 cm), monocular uncorrected and distance corrected near visual acuity (UNVA and DCNVA, at 40 cm), binocular defocus curve and rotational stability. Results Manifest refraction spherical equivalent and refractive astigmatism were −0.24±0.41D and −0.36±0.36D, respectively. About 79% and 97% of eyes were within ±0.50D and ±1.00D, respectively, and 80% and 96% of eyes were ≤0.50D and ≤1.00D of refractive cylinder, respectively. At distance vision, the mean monocular CDVA was −0.02±0.06 logMAR and 92.93% of eyes showed a CDVA of ≥20/20. At intermediate vision, the mean monocular DCIVA values were 0.10±0.07 and 0.17±0.10 logMAR at 80 cm and 66 cm, respectively; and 96.92% and 88.33% of eyes showed a DCIVA of ≥20/32 at 80 cm and 66 cm, respectively. At near vision, the mean monocular DCNVA was 0.31±0.08 logMAR and 75.44% of eyes showed a DCNVA of ≥20/40. The binocular depth of focus range was approximately 1.50D. The mean absolute IOL rotation was 2.73±2.58 degrees with all eyes having a rotation of <10 degrees. Conclusions Eyes with pre-existing astigmatism implanted with the Isopure Serenity toric IOL showed good distance visual acuity and functional intermediate vision, with high refractive accuracy and good rotational stability following cataract and refractive lens exchange surgery.

Visual performance and patient-reported outcomes of a non-apodized diffractive trifocal intraocular lens in Chinese cataract patients: a prospective multicenter real-world study

Bilateral implantation of the PanOptix trifocal IOL provides excellent and early stable visual performance at distance, intermediate, and near in Chinese cataract patients and high refractive predictability and a high rate of spectacle independence are associated with substantial patient satisfaction in real-world clinical practice.

[Evaluation of early clinical outcomes after implantation of monofocal, bifocal, and extended depth-of-focus intraocular lenses].

The subjective and objective visual outcomes after implantation of monofocal, bifocal, and extended depth-of-focus (EDOF) intraocular lenses (IOLs) were compared to compare the subjective and objective visual outcomes after implantation of monofocal, bifocal, and extended depth-of-focus (EDOF) intraocular lenses (IOLs).

Clinical performance of a segmented refractive multifocal IOL: visual outcomes, rotational stability, and the role of higher-order aberrations