TL;DR
This chapter focuses on bacterial antimicrobial resistance, addressing key concepts, major challenges, and emerging technologies within a One Health framework, and framing AMR as a shared ecological and societal responsibility.
Fighting AMR requires more than the development of new drugs alone; it requires a comprehensive approach based on global collaboration, effective regulatory and oversight mechanisms, and strengthened data sharing across institutions.
Antimicrobial resistance (AMR) is one of the most urgent global health threats and is increasingly recognized as a One Health challenge driven by interactions among human, animal, and environmental reservoirs. Central to the emergence and dissemination of AMR across these interfaces are mobile genetic elements (MGEs),...
This review examines the major environmental determinants of AMR-chemical contaminants, water systems, soil and agriculture, wildlife and ecosystems, and climate change and explores mechanisms by which environmental exposures promote resistance, including selective pressures, horizontal gene transfer, and biofilm forma...
The need for cross-sectoral collaboration, innovation, and global policy coherence to mitigate AMR in aquaculture and safeguard food, environmental, and public health security is focused on.
The post-pandemic era offers an important opportunity to strengthen AMR action through a coherent four-pillar framework consisting of governance and national action, stewardship and surveillance, diagnostics, vaccines, therapeutics, and innovation, and public awareness and community engagement.
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