Directed evolution of the Drosophila microbiome improves intestinal health and extends lifespan

THE ROLE OF THE GUT MICROBIOME IN THE DEVELOPMENT AND PROGRESSION OF GASTROINTESTINAL DISEASES: CURRENT EVIDENCE AND FUTURE PERSPECTIVES

The gut microbiome is a complex ecosystem consisting of bacteria, archaea, fungi, viruses, and other microorganisms that interact continuously with the intestinal epithelium, immune system, and metabolic pathways of the host. Increasing evidence demonstrates that alterations in the composition and function of the gut m...

The underexplored mycobiome: insights from Drosophila into human health and disease

Decoding the power of the microbiome in human health

The human microbiota plays a vital role in maintaining physiological homeostasis and overall health. Microbial communities colonize distinct anatomical sites, including the gut, oral cavity, respiratory tract, and skin, where they engage in symbiotic interactions with the host. These site-specific microbial communities...

Gut microbiota dysbiosis remodels the multi-tissue transcriptional landscape of the host

A comprehensive map of the multi-tissue transcriptional landscape shaped by the gut microbiota is provided, which regulate immune response of the gut-liver axis according to inhibit the transcription of Noct, revealing tissue-specific regulatory mechanisms and identifying key genes with potential clinical relevance in...

The human microbiome and its role in health and disease

The human microbiome encompasses trillions of microorganisms, including bacteria, archaea, fungi, viruses, and protozoa, colonizing virtually every body surface. These communities contribute to digestion, immune regulation, metabolic homeostasis, and protection against pathogens. Disruption of microbial balance, termed...

Microbiome and its impact on cardiovascular and renal health

The human microbiome, comprising various microorganisms, is crucial in health preservation and disease development. Recent technological advancements have revealed the microbiome's pervasive presence, challenging traditional notions of bodily sterility. While the microbiome inhabits various body parts, the intestinal t...