This review aims to discuss current and emerging treatment approaches based on modulation of the immune response, with particular emphasis on immune checkpoint inhibitors, targeted therapies, and mRNA vaccines.
Current and emerging treatment approaches based on modulation of the immune response, with particular emphasis on immune checkpoint inhibitors, targeted therapies, and mRNA vaccines are discussed.
Artur Marcysiak, Patrycja Mularczyk, Nina Polek et al.· International Journal of Inn...· 0 citations
Simple Summary Immunotherapy has become an important treatment strategy for patients with advanced melanoma. Melanoma antigen recognized by T cells 1 (MART-1) has been extensively investigated as a target for a variety of immunotherapeutic approaches, including DNA- and peptide-based vaccines, adoptive cell therapies,...
A. Alshevskaya, Sofya Tsarikova, E. Golikova et al.· Cancers· 0 citations
This comprehensive review explores advancements in the treatment of Triple-Negative Breast Cancer (TNBC), emphasizing the transformative impact of targeted therapies and immunotherapies. Given TNBC’s aggressive nature and limited therapeutic options, this review provides an in-depth analysis of emerging strategies that...
Gowhar Rashid, D. Elsori, Zainab Naqvi et al.· Frontiers in Oncology· 0 citations
Overall, TIL therapy constitutes a rapidly evolving and clinically potent treatment modality for melanoma and covers recent advances for improving therapeutic outcomes, including safety optimization, product optimization, next-generation engineered TILs, and predictive biomarkers.
H. Zeng, Wu-Xuan Mei, Chang-Chun Zeng· Current Treatment Options in...· 0 citations
Glioblastoma remains one of the most aggressive and difficult-to-treat brain tumors. Although immunotherapy has transformed the management of several cancers, its clinical impact in glioblastoma has been limited. This review summarizes the main immunotherapeutic approaches currently investigated, including immune check...
D. Slavkov, S. Troyanova-Slavkova· Cancer Immunology Connect· 0 citations
Outline and aim of this thesis
In this thesis, we investigated the determinants of response and resistance to currently used immunotherapy-based regimens in multiple myeloma. We also evaluated novel immunotherapies, including T-cell redirecting therapies and cereblon E3 ligase modulators, in both preclinical and clini...
C. Korst· 0 citations
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