TL;DR
Results suggest that flavonoids, particularly amentoflavone, represent promising scaffolds for the development of antiviral and antioxidant agents against WSSV, warranting further experimental validation.
Karanjin is identified as a promising flavonoid candidate targeting the NDV phosphoprotein, with particularly favorable interactions observed for the phosphoprotein, a key regulator of viral transcription and replication.
Findings provide molecular insights into carotenoid–RdRp interactions and highlight Pandanus conoideus as a valuable tropical source of bioactive compounds for early-stage antiviral research.
In silico pharmacokinetics predict oral bioavailability, rule-of-five compliance, water solubility, and non-toxicity, highlighting Kuwanon D as a promising antibacterial lead.
Findings suggest that bioactive compounds from E. officinalis may serve as promising candidates for the development of anti-CHIKV therapeutics, however, further experimental validation is required to confirm their efficacy and safety.
Computational findings suggest that the tested compounds may serve as preliminary scaffolds for developing quorum-sensing inhibitors targeting LuxR; however, they do not constitute experimental evidence of antibacterial activity.
Findings identify resveratrol as a promising anti-virulence candidate and highlight the utility of integrative computational and experimental strategies for the identification of compounds targeting quorum sensing and biofilm formation inhibition in multidrug-resistant pathogens.
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
