TL;DR
Though not a feature of early or mid-adulthood, declining serum BDNF becomes pronounced in older age, providing a reference point for future studies examining BDNF's relation to cognitive aging and neurodegenerative risk.
Post-stroke cognitive impairment (PSCI) is a common and disabling consequence of stroke. Brain-derived neurotrophic factor (BDNF) plays important roles in neuroplasticity, and the BDNF Val66Met (rs6265) polymorphism may alter cognitive outcomes after stroke; however, evidence remains inconsistent. We searched PubMed, S...
A significant BDNF-mediated pathway was identified in the association between NGAL and cognitive function and in patients with DNS, those with SCI exhibited lower plasma levels of NGAL, BDNF and EGF.
Brain-derived neurotrophic factor (BDNF) plays a crucial role in neuroprotection and neuroplasticity, positioning it as a key target for enhancing rehabilitation outcomes in stroke survivors. This scoping review aimed to explore the relevance of serum BDNF levels in improving trunk control and balance performance among...
Circulating BDNF does not directly establish central BDNF engagement or enhanced neuroplasticity, and current review-level evidence does not establish a universal response, clinical benefit, superior modality, or optimal dose.
Background Brain-derived neurotrophic factor (BDNF) has been proposed as a neuroimmune biomarker of cognitive dysfunction in paediatric neurodevelopmental disorders other than autism spectrum disorder, but two related questions remain poorly characterised: whether circulating BDNF differs between affected and unaffecte...
Background: Postnatal choline supplementation improves memory, non-verbal IQ, executive function, and white-matter microstructure in children with fetal alcohol spectrum disorder (FASD) across randomized controlled trials; however, peripheral and brain biomarkers of these effects are uncharacterized. Methods: We measur...
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