Open access

Functional impact of a type VI secretion system on RsmE-mediated spatial structure formation in Pseudomonas fluorescens Pf0-1

Meghan K. Wells Anton F. Evans Sadhana Srinivasa Amber Delprince Raziel Santos Cole Garland A. Valletta Wook Kim

Jul 2026 · bioRxiv · 0 citations

Medicine Biology

TL;DR

An RsmE-regulated type VI secretion system that kills the invading WT cells and protect the low-density structure is described.

DOI PubMed Semantic Scholar

Read PDF

Similar papers

Open access Sep 2026

Multi-omics insights reveal a divergent type III secretion system-associated secretome in plant growth-promoting rhizobacterial Pseudomonas fluorescens.

The RspL-T3SS axis is established as an integrated regulatory and secretory module that coordinates transcriptional reprogramming with selective protein secretion during root interaction and yields mechanistic insights into bacterial rhizosphere fitness.

Jing Wang, Jia-Wei Hou, Yu-Ling Luo et al. · Microbiology Research · 0 citations

Open access Aug 2026

Flagella are required to activate expression of aggregation factors necessary for T6SS-mediated competition in host-like conditions

A genome-wide transposon mutant screen of the T6SS-wielding beneficial bacterial symbiont, Vibrio fischeri MJ11, and identified two sets of genes that are conditionally required for killing are found, suggesting flagella may play a role in sensing mechanical signals, such as environmental viscosity, to enhance a symbio...

Lauren Speare, Liang Zhao, Morgan N. Pavelsky et al. · mBio · 0 citations

Sep 2026

The Orphan Histidine Kinase TodK Influences Myxococcus xanthus Multicellular Development by Inactivating the CRP/Fnr Homolog, MrpC.

It is found that loss of TodK produces distinct developmental phenotypes that vary with environmental conditions, and quantitative phenotyping approaches can reveal biologically meaningful functions for orphan histidine kinases whose mutant phenotypes might otherwise appear subtle.

Christopher Mataczynski, Maike M. Glaser, S. Huntley et al. · Molecular Microbiology · 0 citations

Open access Oct 2026

The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

Bacteria inhabiting the mammalian gut coexist in dense communities where contact-dependent antagonism mechanisms are widespread. The type VI secretion system (T6SS) is an interbacterial toxin delivery pathway prevalent among gut Bacteroidales, yet its function in naturally evolved microbiomes remains poorly defined. He...

Beth A. Shen, K. Asfahl, Bentley Lim et al. · eLife · 0 citations

Open access Sep 2026

Repression of the Type VI Secretion System (T6SS) During Biofilm Formation Provides a Fitness Advantage for Vibrio cholerae

Conditional T6SS silencing is identified as a potential adaptive strategy that promotes survival within multispecies microbial communities, particularly in environments containing bacteria with highly active or more potent T6SS machineries.

Stephan P. Ebenberger, J. Pombo, Alexander Rechberger et al. · Microorganisms · 0 citations

#protein folding Open access Sep 2026

Identification of genetic determinants that promote biofilm growth under heterotrophic conditions in Cupriavidus necator using transposon enrichment

Results identify B2043 as a negative regulator of biofilm formation acting predominantly during attachment, provide the first experimental evidence for c-di-GMP-dependent biofilm regulation in C. necator H16, and establish a functional-genomics framework — together with eleven further candidate loci — for engineering p...

Janek R. Weiler, C. J. Lapp, Johannes Gescher et al. · Biofilm · 0 citations