The mechanisms involved in NK cells in ovarian cancer treatment, the current status of clinical applications, and new research strategies in the future are summarized to provide a reference for the development of research and clinical practice in this field.
Research directions to make ovarian cancer more susceptible to immunotherapy are moving from empiric treatment to more biologically informed, multimodal approaches aimed at overcoming immune suppression, enhancing antitumor immunity, and personalizing treatment for patients with ovarian cancer.
A. Veneziani, Laura Venegas, A. Oza· Cancer· 0 citations
Cancer remains one of the leading causes of fatal outcome worldwide. Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapeutic
approach to cancer treatment based on the use of cytotoxic lymphocytes engineered to express chimeric antigen receptors. CAR T-cell
therapy involves collecting T-cells from a patie...
K. Aitbayev, I. Murkamilov, V. V. Fomin et al.· Russian Medical Inquiry· 0 citations
This narrative educational review aims to provide a comprehensive overview of recent advances in the understanding of ovarian cancer pathogenesis, the molecular mechanisms driving tumor progression, and the multifaceted role of the immune system in disease development and therapeutic response.
B. Vavrušáková, R. Bartošová, M. Hendrych et al.· Discover Oncology· 0 citations
This review uncovers recent updates on acquired resistance mechanisms toward standard-of-care treatments driven by deeply rooted heterogeneity and aggressive nature and helps to identify novel strategies targeting pathways to reverse resistance and reduce toxicity in breast cancer patients.
Anuveda Sree Samudrala, G. Nagaraju, RamaRao Malla· Biochimica et biophysica act...· 0 citations
Two main ways in which CDK4/6 inhibitors exert their effects are reviewed, one is to directly block the cell cycle, and the other is to reshape the immune microenvironment.
Qi-Ya Jing· International Journal of Bio...· 0 citations
Background/Objectives: Cancer remains a major cause of mortality worldwide, and resistance to therapy continues to limit treatment success. Improving the susceptibility of cancer cells to immune-mediated killing, particularly by natural killer (NK) cells, may enhance therapeutic outcomes. This study aimed to determine...
Tanyarat Pianmak, A. Panya, Natthanich Boonsatit et al.· Pharmaceuticals· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.