Aug 2026· SCIENCE NATURE· Vol 113· 0 citations· 54 references
Medicine
TL;DR
CPEE decreased oxidative stress, colitis pathology, and exhibited an increase in the enzymatic activity of antioxidants and NRF2-related genes, which confirmed that Caulerpa peltata could be used as a possible source for bioactive compounds for further investigation in UC management.
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by intestinal mucosal injury, oxidative stress, and excessive production of pro-inflammatory cytokines. Despite the availability of conventional therapies, long-term treatment is often associated with adverse effects, highlighting...
Objective This study aimed to investigate the therapeutic effects of Pharbitis nil polysaccharides (PNP) on ulcerative colitis (UC) and elucidate the underlying mechanisms. Methods PNP were extracted using water extraction and alcohol precipitation. Acute UC was induced in mice by administration of 3% dextran sulfate s...
Jie Hu, Dan Wu, Ming-Zhu Wu et al.· Natural Product Communicatio...· 0 citations
Ulcerative colitis (UC) is a chronic, relapsing condition with a rising global prevalence. At present, there is a lack of therapeutic strategies that provide both high efficacy and minimal adverse effects. Kaempferol-3-O-glucorhamnoside (KA), a natural compound derived from Thesium chinense Turcz., has demonstrated sig...
Jia-Peng Wang, Chao Chen, Hao-Yu Zhang et al.· International Immunopharmaco...· 0 citations
Findings suggest that Tahiti acid lime (Citrus latifolia) extract represents a promising natural preventive agent against the oxidative stress and inflammatory damage associated with colitis.
Laura Vanessa Zambrano Navarro, Gérman Eduardo Matiz Melo, Renato Arturo Pantoja Guerrero et al.· Revista Vitae· 0 citations
Inflammatory bowel disease, encompassing ulcerative colitis and
Crohn's disease, represents a growing global health burden, characterised by chronic intestinal inflammation, oxidative stress, and progressive mucosal barrier dysfunction. This
study investigated the anti-colitic potential of the whole alkaloid extrac...
Riad Ferhat, Meriem Aziez, M. S. Merakeb et al.· Current Drug Therapy· 0 citations
BACKGROUND
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by aberrant immune activation and intestinal microenvironment dysregulation. Paeoniae Radix Alba (RPA), a classic traditional Chinese medicine (TCM) derived from the roots of Paeonia lactiflora, possesses potent anti-inflammatory,...
Rong-Yun Cao, Mei-Juan Sun, Min Pan et al.· Phytomedicine· 0 citations
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