Aug 2026· Zenodo (CERN European Organization for Nuclear Research)· 3 references
Genomics and Phylogenetic Studies
Abstract
We classify regular full-dimensional stochastic containment among binary standard semi-directed strongly tree-child level-2 phylogenetic networks under the Kimura three-parameter (K3P) model. On the principal positive Fourier domain, a directed containment germ exists if and only if the labelled reduced trees of blobs agree and corresponding complete factors are either labelled-isomorphic or ordinarily triangle-redirected, with coherent boundary transports. The same condition is equivalent to a common full-dimensional regular germ and remains exact in strict continuous time. Thus no proper one-sided containment occurs in the strong class, and the semi-directed topology is generically identifiable and exactly reconstructible outside a proper exceptional set, modulo ordinary triangle redirection. The three ordinary K3P triangle orientations have generic normalized rank 14, share the same irreducible eight-term quartic hypersurface H₁₄ in normalized three-leaf Fourier space, and meet in a common strict continuous-time smooth rank-14 germ. The bounded residue consists of fourteen four-port directed relation orbits—nine polynomially separated and five directed-rank separated—plus two separately separated sink swaps. Exact restoration and coherent one- and two-port probes extend the bounded classification to arbitrary labelled subdivision words. Strong tree-childness is sharp against weakening to weak tree-childness. For every n ≥ 3, two weakly but not strongly tree-child networks have strict continuous-time K3P images sharing a common full-dimensional regular germ of dimension 6n − 3. This is the first Zenodo/DOI-bearing archival release of version 1.0.0 of the complete K3P level-2 classification and its reproducibility evidence. It contains the article, reader supplement, compile-complete source archives, canonical full proof archive, compact verifier, independent-referee replay package, exact manifest, checksums, citation metadata, and a file-level license notice. The deposited bytes correspond to immutable Git commit 0b76dd8e38f262ebe9ba8c1d23281853e334fef2, annotated tag k3p-level2-identifiability-v1.0.0 resolving to that commit, and full-archive SHA-256 4f84417f40b4e5ddae80b36d87dc7bb6d00389a573a58d0b82a2592c9f7c6403. The archive includes the previously completed all-producer regeneration evidence bound to unchanged mathematical inputs, together with successful exact and independently implemented replays, rigorous interval arithmetic where required, and fail-closed mutation tests. The present release changes bibliography, nonmathematical administrative/public-release prose, and release engineering only; unchanged multi-hour mathematical producers were not rerun during this dependency-scoped reseal. No empirical data set is used. Preprint; not peer reviewed by a journal. Generative-AI assistance and its verification workflow are disclosed in the article. Article, supplement, figures, documentation, and mathematical certificate data are licensed under CC BY 4.0; original verifier and build code are licensed under MIT, as mapped in LICENSES.md. No specific funding supported this work. The author declares no competing interests.
Various recent Artificial Intelligence (AI) system failures, some of which have made the global headlines, have highlighted issues in these systems. These failures have resulted in calls for more ethical AI systems that better take into account their effects on various stakeholders. However, implementing AI ethics into practice is still an on-going challenge. High-level guidelines for doing so exist, devised by governments and private organizations alike, but lack practicality for developers. To address this issue, in this paper, we present a method for implementing AI ethics. The method, ECCOLA, has been iteratively developed using a cyclical action design research approach. The method aims at making the high-level AI ethics principles more practical, making it possible for developers to more easily implement them in practice.
Ville Vakkuri, Kai-Kristian Kemell, P. Abrahamsson· EUROMICRO Conference on Soft...· 64 citations· ⚡6
In this paper, we present a novel approach to improving software quality and efficiency through a Large Language Model (LLM)-based model designed to review code and identify potential issues. Our proposed LLM-based AI agent model is trained on large code repositories. This training includes code reviews, bug reports, and documentation of best practices. It aims to detect code smells, identify potential bugs, provide suggestions for improvement, and optimize the code. Unlike traditional static code analysis tools, our LLM-based AI agent has the ability to predict future potential risks in the code. This supports a dual goal of improving code quality and enhancing developer education by encouraging a deeper understanding of best practices and efficient coding techniques. Furthermore, we explore the model's effectiveness in suggesting improvements that significantly reduce post-release bugs and enhance code review processes, as evidenced by an analysis of developer sentiment toward LLM feedback. For future work, we aim to assess the accuracy and efficiency of LLM-generated documentation updates in comparison to manual methods. This will involve an empirical study focusing on manually conducted code reviews to identify code smells and bugs, alongside an evaluation of best practice documentation, augmented by insights from developer discussions and code reviews. Our goal is to not only refine the accuracy of our LLM-based tool but also to underscore its potential in streamlining the software development lifecycle through proactive code improvement and education.
Z. Rasheed, Malik Abdul Sami, Muhammad Waseem et al.· arXiv.org· 62 citations· ⚡3
Molecular dynamics simulations hold great promise for providing insight into the microscopic behavior of complex molecular systems. However, their effectiveness is often constrained by long timescales associated with rare events. Enhanced sampling methods have been developed to address these challenges, and recent years have seen a growing integration with machine learning techniques. This Review provides a comprehensive overview of how they are reshaping the field, with a particular focus on the data-driven construction of collective variables. Furthermore, these techniques have also improved biasing schemes and unlocked novel strategies via reinforcement learning and generative approaches. In addition to methodological advances, we highlight applications spanning different areas, such as biomolecular processes, ligand binding, catalytic reactions, and phase transitions. We conclude by outlining future directions aimed at enabling more automated strategies for rare-event sampling.
Kai Zhu, Enrico Trizio, Jintu Zhang et al.· Chemical Reviews· 54 citations
In agile software development, maintaining high-quality user stories is crucial, but also challenging. This study explores the use of large language models to automatically improve the user story quality in Austrian Post Group IT agile teams. We developed a reference model for an Autonomous LLM-based Agent System and implemented it at the company. The quality of user stories in the study and the effectiveness of these agents for user story quality improvement was assessed by 11 participants across six agile teams. Our findings demonstrate the potential of LLMs in improving user story quality, contributing to the research on AI role in agile development, and providing a practical example of the transformative impact of AI in an industry setting.
Zheying Zhang, M. Rayhan, Tomas Herda et al.· International Conference on...· 48 citations· ⚡4
Systematic literature review (SLR) is foundational to evidence-based research, enabling scholars to identify, classify, and synthesize existing studies to address specific research questions. Conducting an SLR is, however, largely a manual process. In recent years, researchers have made significant progress in automating portions of the SLR pipeline to reduce the effort and time required for high-quality reviews; nevertheless, there remains a lack of AI-agent-based systems that automate the entire SLR workflow. To this end, we introduce a novel multi-AI-agent system designed to fully automate SLRs. Leveraging large language models (LLMs), our system streamlines the review process to enhance efficiency and accuracy. Through a user-friendly interface, researchers specify a topic; the system then generates a search string to retrieve relevant academic papers. Next, an inclusion/exclusion filtering step is applied to titles relevant to the research area. The system subsequently summarizes paper abstracts and retains only those directly related to the field of study. In the final phase, it conducts a thorough analysis of the selected papers with respect to predefined research questions. This paper presents the system, describes its operational framework, and demonstrates how it substantially reduces the time and effort traditionally required for SLRs while maintaining comprehensiveness and precision. The code for this project is available at: https://github.com/GPT-Laboratory/SLR-automation .
Malik Abdul Sami, Z. Rasheed, Kai-Kristian Kemell et al.· arXiv.org· 43 citations· ⚡2
Context: Manual qualitative data analysis is time-intensive and can compromise validity and replicability, affecting analysis design, implementation, and reporting. Large Language Models (LLMs) enable human-bot collaboration in Software Engineering (SE), but their potential for qualitative data analysis in SE remains largely unexplored. Objective: The objective of this study is to design and develop an LLM-based multi-agent system that synergizes human decision support with AI to automate various qualitative data analysis approaches. Methods: We used LLM-based multi-agents systems to assist the qualitative data analysis process, deploying 27 agents, each responsible for a specific task, such as text summarization, initial code generation, and extracting themes and patterns. Results: The main findings are: (1) the LLM-based multi-agent system accelerates the qualitative data analysis process, (2) the system effectively automates tasks such as text summarization, initial code generation, and theme extraction, and (3) the publicly accessible code facilitates validation and further evaluation. Conclusion: The proposed LLM-based multi-agent system automates qualitative data analysis process, creating opportunities for researchers and practitioners. Future improvements focus on enhancing multilingual performance and integrating continuous expert feedback. The source code of proposed system and system details can be found here: https://github.com/GPT-Laboratory/Qualitative-Analysis-with-an-LLM-Based-Agentts
Z. Rasheed, Muhammad Waseem, Aakash Ahmad et al.· arXiv.org· 40 citations
A new method, called CW-Net, translates the reasoning process of an autonomous vehicle’s AI system into understandable concepts that explain its behavior.