DeepWonder3D outperforms state-of-the-art methods in 3D localization accuracy with a tenfold reduction in computational costs, validated by numerical simulations and a hybrid two-photon/light-field imaging system.
A robust, end-to-end pipeline designed to manage and analyze these large-scale volumes efficiently, using a chunk-based data structure (OME-Zarr) to drastically lower hardware memory requirements, enabling the processing of terabyte-scale data on standard workstations.
Chao-Ying Huang, Li-An Chu· Methods in molecular biology· 0 citations
A physics inspired light-field characteristic driven 3D reconstruction network integrating three core innovations: spatial-angular feature blocks for aliasing suppression, multi-scale feature blocks for structural fidelity, and a physics-inspired adaptive weighting loss to ensure high-quality reconstruction of sparse b...
Jing-Fei Hou, Yue Xing, Chu-Qi Yuan et al.· Journal of Physics: Photonic...· 0 citations
Photon noise arising during image acquisition remains a major obstacle to resolving fine structures in optical microscopy, particularly under low-light conditions. Due to the inherent difficulty to obtain noise-free ground truth data, selfsupervised denoising approaches have been widely adopted for microscopy imaging....
Wentao Chen, Zhi Lu· Asia Conference onAsia Confe...· 0 citations
This framework brings whole-brain posterior sampling to low-field super-resolution without sacrificing volumetric accuracy and matches a leading general-purpose regression approach in volumetric accuracy.
Rui W. Yeow, Millie Beament, F. Dick et al.· 0 citations
Recent advances in high-resolution fluorescence and electron microscopy have enabled nanoscale imaging across increasingly large brain volumes, but the resulting terabyte- to petabyte-scale datasets make complete neuronal reconstruction prohibitively expensive in computation, data movement, and manual proofreading. Her...
DeepMoCo is proposed, an innovative deep learning-based framework that integrates a graph neural network (GNN) to establish spatiotemporal feature correlations between biological motion patterns and imaging artifacts and presents a robust and universal solution for high-precision in vivo fluorescence imaging studies.
Shuyue Wang, Rui-Wen Wang, Ge-Lang Hu et al.· PhotoniX· 0 citations
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