Aug 2026· Current Topics in Microbiology and Immunology· 0 citations
Medicine
TL;DR
Effective screening program of risk individuals in endemic populations will allow detection of early-stage NPC that is more amenable to cure utilizing treatment regimen with reduced toxicity while targeting EBV's pathogenic mechanism in NPC will enable the development of novel therapeutic strategy against metastatic and recurrent disease.
Epstein–Barr Virus (EBV) is an oncogenic gammaherpesvirus present in >95% of the adult population. EBV is responsible for nearly 2% of the global cancer burden and is a contributing factor in the development and progression of both epithelial and lymphoid malignancies. Throughout its lifecycle, EBV manipulates the DNA...
Emily DiMaulo-Milk, B. Damania· Viruses· 0 citations
Epstein-barr virus (EBV) and human papillomavirus (HPV) are among the highly prevalent oncogenic viruses. Both can dodge host immune surveillance and reprogram cellular signaling to produce malignancy. For PLWH, long - term immune suppression and steady inflammation amplify these effects, leading to an increasing preva...
Han-Qing Yang· International Journal of Bio...· 0 citations
Epstein-Barr virus (EBV) is an oncogenic DNA virus that is etiologically associated with multiple malignancies, including nasopharyngeal carcinoma, gastric carcinoma, and lymphomas. Although EBV encodes numerous viral microRNAs (miRNAs), the pathogenic functions of individual miRNAs remain incompletely characterized. I...
Epstein-Barr virus (EBV) infects 90% of the population worldwide and is associated with multiple malignancies, including Burkitt, Hodgkin and post-transplant lymphomas, nasopharyngeal and gastric carcinoma. EBV also triggers autoimmune diseases, including multiple sclerosis and systemic lupus erythematosus. While host...
Hong-Bo Wang, Y. Y. Yeo, Chong Wang et al.· bioRxiv· 0 citations
Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) remains a clinically challenging malignancy, particularly in recurrent or metastatic disease where durable responses to chemoradiotherapy and immune checkpoint blockade are limited. The viral aetiology of NPC provides a strong biological rationale for i...
N. Allehyani, Mohammed Alissa, Abdullah Alghamdi et al.· Reviews in Medical Virology· 0 citations
