Synthesis and characterization of beta-tricalcium phosphate /polyacrylic acid composite membrane
TL;DR
The β-TCP/PAA membrane exhibited promising structural and chemical properties, supporting its potential as a novel GBR membrane for periodontal tissue regeneration.
Abstract
Background: Untreated bone loss can lead to serious complications. Guided Bone Regeneration (GBR) is a promising approach for treating periodontal tissue and alveolar bone defects, in which membranes serve as protective barriers for bone grafts. Purpose: This study aimed to fabricate and characterize a novel membrane composed of β-tricalcium phosphate (β-TCP) and polyacrylic acid (PAA) for potential GBR applications. Methods: β-TCP powder was synthesized using a Ca/P ratio of 1.5 from calcium carbonate and dibasic calcium phosphate dihydrate, followed by ball milling and sintering. The β-TCP membrane was then fabricated by combining β-TCP with PAA at various concentrations. The fabricated membranes were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). Results: XRD analysis confirmed the presence and stability of the crystalline β-TCP structure within the membrane. SEM revealed closely packed β-TCP particles with strong interparticle bonding. FTIR analysis demonstrated chemical interactions between the carboxyl (-COOH) groups of PAA and calcium ions (Ca²⁺) from β-TCP, indicating successful integration of the two components. Conclusion: The β-TCP/PAA membrane exhibited promising structural and chemical properties, supporting its potential as a novel GBR membrane for periodontal tissue regeneration.