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Mitral Annular Calcification and Its Severity in Relation to Left Atrial Reservoir Strain and a Non‐Invasive Left Atrial Stiffness Index

Aug 2026 · Echocardiography · Vol 43 · 0 citations · 28 references
Medicine

TL;DR

MAC and its severity were associated with impaired LA reservoir function and a higher non-invasive stiffness index, and the index did not discriminate MAC better than its simpler components, so these cross-sectional findings are hypothesis-generating.

Abstract

Mitral annular calcification (MAC) is associated with atrial fibrillation and diastolic dysfunction, but its relationship with left atrial (LA) mechanics is poorly defined. The ratio of E/e′ to LA reservoir strain (LASr) is a non‐invasive surrogate of, not a direct measure of, LA stiffness. We assessed MAC and its severity against LASr and this LA stiffness index (LASI).

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