Aug 2026· Echocardiography· Vol 43· 0 citations· 28 references
Medicine
TL;DR
MAC and its severity were associated with impaired LA reservoir function and a higher non-invasive stiffness index, and the index did not discriminate MAC better than its simpler components, so these cross-sectional findings are hypothesis-generating.
Abstract
Mitral annular calcification (MAC) is associated with atrial fibrillation and diastolic dysfunction, but its relationship with left atrial (LA) mechanics is poorly defined. The ratio of E/e′ to LA reservoir strain (LASr) is a non‐invasive surrogate of, not a direct measure of, LA stiffness. We assessed MAC and its severity against LASr and this LA stiffness index (LASI).
Left atrial strain imaging provides a robust non-invasive predictor of LAA dysfunction in severe rheumatic MS patients in sinus rhythm and supports the potential clinical utility of LA strain in improving risk stratification and guiding anticoagulation decisions in this under-recognized high-risk population.
J. Yusuf, Gaurav Sharma, Ankit Bansal et al.· European Heart Journal Open· 0 citations
In individuals free of overt cardiovascular disease, MRI-derived LV filling dynamics were associated with structural alterations of the left atrium and pulmonary vasculature, suggesting that changes across the cardiopulmonary axis may already be detectable by whole-body MRI before clinical disease becomes apparent.
C. Wintergerst, R. Lorbeer, S. Rospleszcz et al.· Frontiers in Cardiovascular...· 0 citations
Age and sex-relatedMitral annular calcification is age and sex-related and is significantly associated with structural features of a diastolic impairment profile, and may warrant focused management of diastolic dysfunction and systemic metabolic risk.
Israel Gotsman, Ruth Shnipper, D. Zwas et al.· American Journal of Cardiolo...· 0 citations
Recognizing this high-risk phenotype supports closer ambulatory rhythm monitoring to allow timely arrhythmia detection and subsequent initiation of anticoagulation to prevent thromboembolic events.
Left and right atrial stiffness are both associated with adverse outcome in DCM and add prognostic information to an LV-centred risk model, and their unweighted sum offers a single parsimonious measure.
A. Vijiiac, I. Petre, S. Onciul et al.· Journal of Clinical Medicine· 0 citations
In patients with DMR, AF was associated with more advanced LA structural remodeling, impaired LA function, and higher CMR LGE burden, and echocardiographic LA functional parameters may provide complementary information for the discrimination of AF.
X. Li, Y. Song, Y. Hu et al.· medRxiv· 0 citations
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