Skip to content
Case report Open access

Transcatheter Tricuspid Valve Replacement in High-Risk Elderly Patients: Procedural Feasibility, Complexity, and Delayed Conduction Disturbances.

Sep 2026 · JACC Case Reports · pp. 110532 · 0 citations · 9 references
Medicine

TL;DR

The feasibility of TTVR in elderly patients with complex anatomy is demonstrated and effective in selected elderly high-risk patients with severe TR and challenging anatomy and delayed conduction disturbances as a clinically important complication requiring extended rhythm surveillance are highlighted.

Abstract

Background

Severe tricuspid regurgitation (TR) is associated with substantial morbidity and mortality and remains undertreated in elderly patients with prohibitive surgical risk. Transcatheter tricuspid valve replacement (TTVR) has emerged as a therapeutic option for anatomies unsuitable for transcatheter edge-to-edge repair. CASE SUMMARY We report 2 elderly high-risk patients with torrential symptomatic TR who underwent orthotopic TTVR using transfemoral venous access. The first patient, a 94-year-old woman with prior mitral annuloplasty and a transvalvular pacemaker lead, underwent successful TTVR with complete elimination of TR and rapid symptomatic improvement. The second patient, an 84-year-old man with severe leaflet tethering and complex anatomy, underwent successful valve implantation but subsequently developed delayed complete atrioventricular block requiring leadless pacemaker implantation.

Discussion

These cases demonstrate the feasibility of TTVR in elderly patients with complex anatomy and highlight delayed conduction disturbances as a clinically important complication requiring extended rhythm surveillance. TAKE-HOME MESSAGES TTVR is feasible and effective in selected elderly high-risk patients with severe TR and challenging anatomy. Delayed conduction abnormalities may occur several days after implantation and warrant structured rhythm monitoring.

Read PDF

Similar papers

Case report Open access Sep 2026

Transcatheter Tricuspid Valve Replacement for Torrential Tricuspid Regurgitation in Complex Adult Congenital Heart Disease

Background Severe tricuspid regurgitation (TR) carries high morbidity and is often undertreated in patients with complex congenital heart disease and prohibitive surgical risk. Case Summary A 33-year-old woman with complex congenital heart disease and multiple prior surgeries presented with progressive right-sided hear...

Emily Morris, Ali B. Roomi, M. Costello et al. · 0 citations
Case report Open access Sep 2026

Successful Surgical Tricuspid Valve Repair of Severe Recurrent Tricuspid Regurgitation After Transcatheter Edge-to-Edge Repair

Background Transcatheter edge-to-edge repair has emerged as a minimally invasive option for patients at high surgical risk. Residual/recurrent tricuspid regurgitation (TR) is associated with high morbidity and mortality. Case Summary A 79-year-old woman developed recurrent severe TR after initially successful TriClip i...

A. Winkler, Katja Gansterer, E. Boxhammer et al. · 0 citations
Case report Open access Sep 2026

Transcatheter Edge-to-Edge Mitral Valve Repair for Severe Degenerative Mitral Regurgitation With Coexisting Cor Triatriatum Sinistrum.

BACKGROUND Cor triatriatum sinistrum (CTS) is a rare congenital malformation, and its coexistence with degenerative mitral regurgitation (MR) in older adults is exceptionally rare and creates substantial technical challenges for transcatheter interventions. CASE SUMMARY We report a 78-year-old woman presenting with p...

Shi-Cheng Li, Yu-Bao Hu, Jie Shen et al. · 0 citations
Case report Open access Sep 2026

Transapical Mitral TEER and Aortic Regurgitation TAVR With Dedicated Device in a Patient With Extreme Scoliosis

Background Concomitant aortic and mitral regurgitation (CAMR) is a rare valvulopathy, seen in patients with scoliosis, and rarely involves aortic regurgitation with concomitant primary mitral regurgitation associated with poor prognosis when left untreated. Current guidelines lack robust evidence to guide the managemen...

Dominador V. del Castillo, Bin Wang, Yan Wang · 0 citations
Case report Open access Sep 2026

Transjugular LuX-Valve Plus transcatheter tricuspid valve replacement for torrential tricuspid regurgitation in a patient with a giant right atrium and multiple prior valve interventions: a case report

Abstract Background Transcatheter tricuspid valve replacement (TTVR) is an option for selected patients with severe tricuspid regurgitation (TR) who are at high surgical risk, but experience remains limited in those with extreme right-heart anatomy, including a giant right atrium and a markedly enlarged elliptical tric...

Qun-Tai Qiu, Xin-Lei Wu, Dao-Zhu Wu et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.