TL;DR
Evaluation of expression profiles of miR-155 and miR-326 together with the serum of IL-17A and IL-23 in patients with essential hypertension found that these biomarkers may reflect distinct aspects of hypertension-associated inflammation.
Introduction and aim. Essential hypertension (EH) is a major cardiovascular risk factor worldwide. The interleukin (IL)-17 and IL-23 axis is a key driver of Th17-mediated immune response; however, the involvement of microRNAs in modulating this axis in patients with essential hypertension remains poorly understood. Thi...
Hypertension (HTN) is the leading modifiable risk factor of cardiovascular diseases. Implicated immunological mechanisms are of great interest nowadays. This study aimed to assess the role of B cells by measuring serum immunoglobulin (IgG) and IgM levels, regulatory T cell levels, and interleukin (IL)-10 levels in hype...
Adipokines and inflammatory cytokines play a key role in the regulation of metabolic, inflammatory, and cardiovascular processes. Their involvement in the pathogenesis of arterial hypertension (AH) opens up new opportunities for understanding the mechanisms of disease development and developing personalized approache...
Background: Coronary artery disease (CAD) accounts for major morbidity and mortality worldwide. Objectives: This study was designed to investigate the expression level of miR-126 in the patients with CAD as well as to verify choosen inflammatory and biochemical parameters related to the disease. The study also examined...
INTRODUCTION Osteoporosis is a metabolic disorder characterized by reduced bone mass and microarchitectural deterioration, and it is closely associated with inflammatory processes. This study investigated the expression of microRNA-146a (miR-146a), interleukin-31 (IL-31), and interleukin-33 (IL-33) in osteoporosis and...
Elevated ET-1, IL-6, and IL-18, along with ET-1 polymorphism, suggest synergistic genetic-inflammatory mechanisms in CAD progression among diabetic-hypertensive patients and multi-marker profiling improves early CAD detection.
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