Finerenone Alleviates Cardiac Microvascular Injury and Neutrophil Extracellular Traps Formation in Diabetic Cardiomyopathy via Regulating AKT1 Phosphorylation

Exercise-Mediated Regulation of Ferroptosis in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Perspectives

Exercise is an important non-pharmacological intervention for the prevention and management of diabetes and its cardiovascular complications; however, the underlying mechanisms by which exercise confers cardiometabolic protection remain incompletely understood. Diabetic cardiomyopathy (DCM) is a major cardiovascular co...

Mitochondrial YME1L Restrains GRP75-Dependent ISR Activation to Prevent Podocyte Senescence in Diabetic Kidney Disease.

ARTICLE HIGHLIGHTS Loss of YME1L promotes podocyte senescence in diabetic kidney disease. YME1L deficiency induces sustained maladaptive integrated stress response activation. YME1L interacts with and regulates mitochondrial GRP75 homeostasis. GRP75 accumulation drives persistent integrated stress response activation a...

Ginsenoside Rb Group in Chronic Heart Failure: Emerging Insights into Mitochondrial Quality Control, Autophagy and Ferroptosis

This poster focuses on the part of the central nervous system that is affected by CHF and focuses on the part of the immune system that is affected by CHF.

Cardiac Macrophage-specific circHIPK2: a New Regulator of Post-infarction Inflammation and Cardiac Remodeling

Eupatilin Alleviates Acute Myocardial Ischemia‐Reperfusion Injury in Rats via the Akt/GSK‐3β Pathway by Targeting COXs

Eupatilin confers cardioprotection against myocardial ischemia‐reperfusion injury (MIRI). Cyclooxygenases (COXs) serve as key rate‐limiting enzymes for prostaglandin biosynthesis. This study investigated the effects of eupatilin on COXs.

Cell‐Type‐Specific HSPA1B Expression Links COPD and Atherosclerosis

Chronic obstructive pulmonary disease (COPD) and atherosclerosis frequently coexist, but their shared immune mechanisms remain incompletely understood.