Neuromodulation for drug-resistant epilepsy is associated with modest improvements in depression and quality of life without meaningful cognitive deterioration over follow-up durations of 6 months to 14 years.
Thalamic neuromodulation using DBS and RNS was safe and well tolerated in pediatric patients with DRE, including multifocal and generalized seizure onsets, with a trend toward greater benefit in the DBS group.
Dominic Nistal, Benjamin D. Edmonds, Adriel Barrios-Anderson et al.· Journal of Neurosurgery: Ped...· 0 citations
Implantable VNS was associated with higher 1-year clinically meaningful improvement and greater longitudinal CRS-R gains than conservative management in DoC patients with epilepsy and to explore factors related to response.
J. Zuo, K. Ma, Zi-Zhang Cheng et al.· Therapeutic Advances in Neur...· 0 citations
Current randomized evidence suggests that rTMS and tDCS may improve depressive symptoms in patients with PSD and appear generally well tolerated, however, the certainty of these findings is limited by substantial heterogeneity, small sample sizes in several trials, and variation in stimulation protocols.
Pei-Zhang Huang, Hao-Jie Wang, Chen Huang et al.· Frontiers in Psychology· 0 citations
DBS represents an important therapeutic option for DRE, expanding the scope of neuromodulation beyond traditional surgical approaches and further studies are required to refine patient selection, improve targeting strategies, and optimize stimulation paradigms.
Ryota Sasaki, Masako Kinoshita, Abbas F. Sadikot et al.· Frontiers in Neurology· 0 citations
Peripheral nerve stimulation was associated with short-term reduction in tremor severity and functional impairment in patients with ET, with an overall acceptable safety profile, suggesting that it may serve as a middle ground option between pharmacotherapy and invasive neurosurgical approaches.
Mark Messak, Y. Omar, Nada Mosad et al.· Neurosurgical review· 0 citations
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