It is hypothesized that selected homeostatic gene-expression states may be partially restored in experimental cancer models through the integration of quantum-informed AI, CRISPR gene alteration, and nanomaterial delivery, which could support future cancer therapies that move beyond tumor suppression toward controlled modulation of malignant cell states, although substantial preclinical and clinical validation remains necessary.
The significance of the CRISPR/Cas9 genome editing system in the treatment of bladder cancer is emphasized and significant promise exists for improving the therapeutic potential of CRISPR-Cas9 technology and addressing complex cancer therapy difficulties because of the rapid development of nanotechnology-based delivery...
Swarupananda Mukherjee, D. Karati, Sinjini Sarkar et al.· Nanomedicine· 0 citations
The mechanisms of CRISPR/Cas action and its applications in hematologic malignancies, breast cancer, colorectal cancer, gastric cancer, and lung cancer are explored.
M. Omarov, E. Karacheva, M. M. Arapieva et al.· Сибирский научный медицински...· 0 citations
The mechanisms of CRISPR-Cas9 gene editing, recent technological advancements, and prospects for cancer management are explored and insights into strategies for precise delivery, improved targeting accuracy, and the regulatory considerations surrounding CRISPR-Cas9 for oncological applications are provided.
Nikhil Rawal, Shruti Batra, Tanu Sharma et al.· Current pharmaceutical desig...· 0 citations
An overview of the CRISPR screen methodology, which involves introducing guide RNAs targeting specific genes into cells, followed by phenotype selection and analysis, is presented, providing valuable insights into gene function and potential therapeutic targets.
Xinyue Zhou, Rui Lu· Methods in molecular biology· 0 citations
The strategies detailed here define a next-generation precision-oncology paradigm capable of anticipating tumor evolution, overcoming resistance, and preventing metastatic relapse, by uniting AI-guided design, circadian reprogramming, dormancy eradication, and logic-gated delivery.
Anmar Ghanim Taki, Abdulkareem Shareef, Vimal Arora et al.· Iranian Journal of Basic Med...· 0 citations
Overall, CRISPR-based technologies show considerable potential to support precision oncology in prostate cancer by enabling molecularly informed therapeutic strategies and addressing treatment resistance, although challenges related to delivery, off-target effects, tumor heterogeneity, immunogenicity, and clinical tran...
Vaibhavkumar Patel, Pratichi Singh, S. Dutta et al.· Critical reviews in oncology...· 0 citations
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