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Open access

Sources of Variability in Normative Cerebral [18F]FDG-PET imaging

Giordana Salvi de Souza G. Povala G. G. S. Peixoto A. Coutinho A. Bieger M. Rozalem-Aranha M. D. de Bastiani E. Zimmer W. Borelli L. W. de Souza
Aug 2026 · bioRxiv · 0 citations · 31 references
Medicine Biology

TL;DR

Cortical gray matter provides the most stable reference region and supports harmonized, covariate-adjusted normative datasets for clinical and research applications and is the major sources of variance in brain [¹⁸F]FDG-PET quantification in CN subjects.

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