Water-Mediated Synthesis, Antimicrobial Evaluation, Molecular Docking, and ADMET Profiling of Novel 2-Amino-3,5-dicarbonitrile-6-sulfanylpyridines

Sudha Rasmi Sudabattula R. S. R. Dachuru Mohan Gundluru Kranthi Kumar Konidala S. Yeguvapalli

Aug 2026 · Russian journal of bioorganic chemistry · Vol 52 · 0 citations · 51 references

TL;DR

The seamless integration of green synthesis, computational modeling, and biological validation highlights these 2-amino-3,5-dicarbonitrile-6-sulfanylpyridine hybrids as compelling lead candidates for multi-target therapeutic applications against invasive bacterial and fungal infections.

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