TL;DR
It is suggested that alcohol consumption is associated with increased GC risk in a dose-response manner, and recommendations to limit alcohol consumption for cancer prevention are supported.
Alcohol intake frequency was associated with increased risk of oral and pharyngeal cancer, and the number of drinks per week was linked to increased stomatitis risk, suggesting an independent effect of alcohol consumption on stomatitis risk under MR assumptions.
The aim of this study was to clarify the relationship between ACI and blood pressure.
In this nationwide cohort of 3,869,084 adults, heavy alcohol consumption was associated with increased HCC risk in the 40–59-years and ≥60-years age groups, with the strongest association and highest 10-year cumulative risk observed among heavy drinkers aged ≥60 years.
There was little evidence of an overall association between alcohol intake and stomach cancer risk, although modest positive associations were observed among never smokers and in Asian cohorts.
Among individuals 40 years and older, frequent-heavy drinking was associated with a higher risk of stroke, while low-to-moderate regular drinking might be associated with a lower all-cause mortality risk compared to low drinkers.
Adolescent smoking was associated with a modest increase in breast cancer risk, whereas no clear association was observed for adolescent alcohol consumption, and the potential value of smoking prevention during adolescence is highlighted.
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