It is indicated that syringic acid exerts peripheral antinociceptive and anti-inflammatory activities and acute administration of syringic acid did not induce gastric ulceration in mice.
Şeyda Yön, Cevşen Yazıcı Şenocak, Gizem Türkoğlu Sağlık et al.· ACS Omega· 0 citations
Evaluation of analgesic and anti-inflammatory activity demonstrated that test compound 1, significantly prolonged response latency in the hot plate method, reduced the number of abdominal writhes induced by 1% acetic acid, decreased carrageenan- and formalin- and formalin-induced paw edema, and reduced the volume of ex...
Girish A. Hampannavar, N. Jeedi· Ankara Universitesi Eczacili...· 0 citations
The findings suggest that OA possesses pronounced antinociceptive and anti-inflammatory properties, however, the reduced efficacy observed with combined administration and the elevation of cytokines indicate that OA and LA might work via different pathways, thus warranting further investigation into their dose-dependen...
A. Öner, Esin Akarsu Orunç· The Veterinary Journal· 0 citations
This research provides the first evaluation of LINS01022's analgesic efficacy and its favourable safety profile in neuropathic pain, and suggests that a novel H3R antagonist is a promising drug candidate and a valuable pharmacological tool for further investigation.
Magdalena Maciuszek, M. Białoń, Mateusz Królewski et al.· European Journal of Pharmaco...· 0 citations
The studied compounds of the indenopyrrole series and their indenopyridazine derivatives are virtually non-toxic compounds, exhibit an anti-inflammatory effect and reduce the severity of pain associated with inflammation.
O. N. Gein, N. V. Nosova, E. Chizhova et al.· Acta Biomedica Scientia· 0 citations
Azilsartan exhibits significant anti-inflammatory and inflammation-associated pain–modulating effects in preclinical models, but does not demonstrate significant analgesic activity in acute thermal nociception.
S. Atal, Santenna Chenchula, P. Ponmani et al.· Beni-Suef University Journal...· 0 citations
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