Jun 2026· Journal of Mycology and Infection· pp. 80· 0 citations
TL;DR
This study investigated the first confirmed case of eumycetoma, and a brief comparative analysis of various molecular diagnostic tests currently used for diagnostic confirmation was performed.
Abstract
Mycetoma is a type of chronic granulomatous infection that affects the skin and subcutaneous tissue, typically resulting from the traumatic inoculation of the causative organism. Typically, this disease is limited to the countries located in the subtropical zone. It is conventionally diagnosed based on certain typical direct microscopic features of grains and culture properties. However, the sensitivity and specificity of these tests are highly variable, apart from being time-consuming, invasive, and subjective. The rapid establishment of the identity of the causative organism, along with its drug susceptibility, plays an important role in the management of mycetoma to avoid complications and side effects associated with the long-term use of currently available drugs. Notably, cases of mycetoma have not
been reported in Kuwait. This study investigated the first confirmed case of eumycetoma, and a brief comparative analysis of various molecular diagnostic tests currently used for diagnostic confirmation was performed.
The first documented pediatric cutaneous pseudomyiasis case associated with a psychodid larva in Italy is reported, consistent with an incidental recovery of a psychodid larva and support an interpretation of pseudomyiasis rather than true myiasis.
B. Moroni, M. D. Di Nicola, Alberico Franzin et al.· Parasitologia· 0 citations
An unusual instance of chromoblastomycosis caused by F. pedrosoi in a woman from South Kerala with a preceding history of a leech bite is described, highlighting the importance of combining clinical examination, histopathology, fungal culture, and molecular sequencing for accurate diagnosis and effective management of this rare and chronic fungal infection.
Ashna Ajimsha, Neeraja C. K., Kiran Subhash· Journal Of Vocational Health...· 0 citations
The article summarizes and analyzes modern scientific data on the epizootological and clinical features of American foulbrood (AFB) of bees, the causative agent of which is the spore-forming bacterium Paenibacillus larvae. The historical aspects of the study of the disease, the biological properties of the pathogen, itʼs high resistance in the environment and the ability to maintain infectivity for a long time are highlighted. The ERIC I–V genotypes, their prevalence and differences in virulence are characterized. Based on WOAH (WAHIS) and ProMED data, the modern epizootic situation in the countries of Europe, Asia, Africa and America is analyzed, which indicates the global spread of the disease and its significant economic impact on the beekeeping industry. Typical clinical signs of AFB are described, in particular, variegation of brood, sunken cell lids, the presence of a viscous putrefactive mass and the formation of dense scales. Modern approaches to laboratory diagnostics are considered, including microscopic, bacteriological and molecular genetic methods with an emphasis on the high sensitivity of PCR for early detection of the pathogen. The main preventive measures are summarized, which include compliance with veterinary and sanitary standards, regular monitoring of apiaries, control of bee movements and timely elimination of dysfunctional colonies, which are key to preventing the spread of American foulbrood.
M. Karpulenko, Y. Storchak, V. Postoienko et al.· One Health Journal· 0 citations
Tintelnotia destructans is a recently described fungus within the family Phaeosphaeriaceae, previously reported only in superficial human infections such as keratitis, onychomycosis, and non-invasive sinus fungus ball. We describe the first case of invasive rhinosinusal infection due to this pathogen in a child with severe aplastic anemia. Diagnosis was established by histopathology showing submucosal fungal invasion and broad-range fungal PCR targeting 18S rRNA identifying T. destructans. Combined endoscopic surgical debridement, antifungal therapy (liposomal amphotericin B and isavuconazole) and immune reconstitution after emergency haplo-identical hematopoietic stem cell transplant ultimately led to complete recovery without recurrence 18 months after treatment, despite continued therapeutic immunosuppression for GvHD. This case expands the known pathogenic spectrum of T. destructans, demonstrating its potential to cause invasive disease in severely immunocompromised hosts. Advances in molecular diagnostic tools may expand the spectrum of fungi causing invasive fungal infections by identification of novel pathogenic species.
Manon Jaboyedoff, F. Lamoth, C. Bertelli et al.· Open Forum Infectious Diseas...· 0 citations
Generalised demodicosis may predispose dogs to secondary Malassezia overgrowth through disruption of the skin barrier and alteration of local immune responses, while antifungal susceptibility testing may assist in selecting appropriate therapy.
Rasamalla Suresh, P. Mallesh, R. P. et al.· Journal of Advances in Micro...· 0 citations
K. ohmeri was successfully identified using Vitek-2, MALDI-TOF, and ITS (Internal Transcribed Spacer) area sequencing, while the Integral System Yeast Plus misidentified the isolate as Candida tropicalis.
Siti Nadliroh, Mardiastuti Wahid, Fithriyah Sjatha et al.· 0 citations
