Jul 2026· European Journal of Clinical Microbiology and Infectious Diseases· 0 citations· 7 references
Medicine
TL;DR
Findings demonstrate the stability, safety, and therapeutic efficacy of bacteriophages EAS1 and EAS2, particularly EAS2, supporting phage therapy as a promising alternative approach for the treatment of MRSA infections.
The emergence of antibiotic-resistant pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA), represents a major public health threat, with limited treatment options. Bacteriophage-derived endolysins and their engineered chimeric derivatives have attracted attention as alternative antibacterial agen...
Sarvenaz Janbaz, Amir Savardashtaki, Marziyeh Asadi et al.· Biotechnology and applied bi...· 0 citations
The potential of SAP_2 as a biocontrol candidate for controlling MRSA contamination in milk is supported and good biosafety and reduced bacterial burdens in MRSA-infected mice are exhibited.
Dong-Xin Ma, Shuai-Feng Gu, Yu-Qiang Zhang et al.· Current Research in Food Sci...· 0 citations
Suggestion that in vitro evaluation of MMRP1 and MMRP4 are highly recommended to more deeper future experimental studies to combat MDR E. cloacae nosocomial infections supported by genomic foundation and eventually, the possibility to be suitable for phage-engineering applications in clinical settings is highlighted.
Mohammad S. A. Al-Obaidi, M. T. Al-Ouqaili, F. Al-Marzooq· Frontiers in Microbiology· 0 citations
This is the first biologically and genomically characterized S. aureus phage from Bangladesh with demonstrated activity against MDR MRSA biofilms, highlighting its potential as a promising candidate for controlling device‐associated MRSA infections.
Raphael Kabir Niloy, Shakhinur Islam Mondal, Nurnabi Azad Jewel et al.· International Journal of Mic...· 0 citations
ABSTRACT Staphylococcus aureus infections pose a significant threat to global human health, particularly with the widespread transmission of methicillin-resistant S. aureus (MRSA) strains, which has created an urgent need for the development of new antimicrobial agents. PFM01 is an N-alkylated derivative of Mirin, an M...
Cong-Cong Li, Xuan-Cheng Huang, Ke-Wei Fan et al.· Microbiology spectrum· 0 citations
A theoretical foundation for the clinical translation of MRSA prophages is established, positioning Lys81 as a novel candidate for treating drug-resistant bacterial infections.
Fang-Fei Ran, Ming-Lei Yang, Xiu-Xiu Zeng et al.· Frontiers in Microbiology· 0 citations
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