Endophytic fungus Muyocopron dipterocarpi isolated from Catharanthus roseus as a novel producer of ajmalicine and other metabolites: insights from HPLC and LC-HRMS analysis
Aug 2026· Antonie van Leeuwenhoek· Vol 119· 0 citations· 72 references
Medicine
TL;DR
Using LC-HRMS for comprehensive profiling of fungal metabolites, several indole alkaloids from Muyocopron dipterocarpi are identified for the first time, including gelsemicine, ajmalicine, brassitin, and geissospermine.
Endophytic fungi are recognized as a rich source of structurally diverse secondary metabolites. However, the metabolite composition of endophytic fungi associated with the endemic medicinal plant Curcuma sumatrana Miq. remains largely unexplored. This study aimed to profile the major metabolites present in the dichloro...
Khiratul Azizi, Nova Syafni, D. Handayani· Journal of Community Health...· 0 citations
Introduction Ardisia crenata Sims is an important medicinal plant in southern China, yet its industrial utilization is severely limited by unsustainable harvesting of wild resources, inconsistent active ingredient quality, and inefficiencies in conventional extraction processes. Endophytic fungi, which can produce bioa...
Chang Liu, De-Mei Yang, Jiang-Li Luo et al.· Frontiers in Microbiology· 0 citations
The study aimed to isolate and identify endophytic fungi from Enhydra fluctuans leaves and evaluate their secondary metabolites and biological activities. A fungal isolate EF-1 was cultivated on rice medium and extracted separately with ethyl acetate (EA), methanol, and n-hexane. All extracts were subjected to phytoche...
Ahadul Putra, Bali Yana Fitri, Juli Supriyanti et al.· Journal of Applied Pharmaceu...· 0 citations
Results position F. oxysporum (A1/APFE1) and A. niger (E2/RSFE2) as promising candidates for the development of novel antimicrobial agents, highlighting the edible plant-associated endophytic fungi’s unrealized medicinal potential.
H. M. Farouk, F. M. Gaber, A. Al-Karmalawy et al.· Archives of Microbiology· 0 citations
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