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Open access

DHX36 regulates antral follicle development and ovulation as a non-OSF maternal factor by maintaining oocyte homeostasis and supporting OSF delivery

Yu-Xuan Jiao Fangying Sun Guo-Wei Bu Yulan Chen Kun-Peng Zhou Bo-Ya Guo Hai-Teng Deng Yizhen Sima Hongying Sha Suying Liu Yong-Juan Sang Qiming Sun Xiaona Chen Hua-Ting Wang Cun-Qi Ye Heng-Yu Fan
Aug 2026 · bioRxiv · 0 citations · 54 references
Biology

TL;DR

Findings establish DHX36 as a maternal regulator that links oocyte intrinsic homeostasis to intercellular communication, suggesting that DHX36-dependent maintenance of membrane and organelle integrity is essential for OSF delivery, cumulus cell function, antral follicle development, and ovulation.

DOI Semantic Scholar
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