Aptamer-functionalized aggregation-induced emission micelles for integrated detection and photodegradation of lipopolysaccharides.

Arginine-engineered gold nanoclusters for doxorubicin chemiluminescence sensing

A straightforward, rapid, and highly sensitive biosensor has been developed for the detection of doxorubicin (DOX) in human serum samples, achieving a low detection limit of 0.029 µM.

Integrated Colorimetric/Fluorescence Nanozyme Dual-Signal Probe for Simultaneous Detection and Degradation of Organophosphorus Nerve Agents.

Independent and Efficient Pyridone Scaffold: Universal Afterglow Chemiluminescence Platform for High-Contrast Bioimaging.

An independent and efficient pyridone scaffold is reported for constructing afterglow molecules and an activatable afterglow chemiluminescence probe was developed, which can simultaneously activate fluorescence and afterglow signals in the presence of peroxynitrite, and is successfully applied for the precise diagnosis...

Electrochemical aptasensor based on DNA nanoflowers for the sensitive detection of acrylamide.

As a prevalent heat-induced byproduct, acrylamide (AA) is frequently generated during thermal food processing, particularly in baked and fried goods. It is a Group 2A carcinogen produced via the Maillard reaction and exhibits neurotoxicity as well as reproductive and developmental toxicity. In this work, DNA nanoflower...

Rapid Broad-Spectrum Colorimetric Detection of Bacteria Using Polylysine-Mediated Gold Nanoparticle Aggregation.

Rapid on-site detection of bacterial contamination remains an urgent need in public health and environmental monitoring. Herein, we report a one-step, label-free colorimetric sensor for broad-spectrum bacterial detection based on a competitive electrostatic mechanism. Cationic poly-l-lysine (PLL) induces the aggregatio...

A Ce-Involved MOF@Nanozyme Probe Empowers Programmable Centrifugal Microfluidics for Integrated Immunoassay.

Pathogenic bacteria pose significant threats to public health, and their rapid and sensitive detection methods are urgently needed. Here, we developed a hybrid metal-organic framework nanozyme (Ce/Zr-UiO 66@CeO2) with high peroxidase-like activity for colorimetric biosensing that was integrated into a programmable cent...