It is suggested that vitamin E may help limit the harmful effects of long-term glyphosate exposure in animals and could serve as a simple, protective dietary supplement.
Abstract
Simple Summary Glyphosate is the most widely used weed killer in the world. Farm animals, companion animals, and working animals can be exposed to it over long periods through feed, water, and grazing on treated pasture, which makes its safety a genuine veterinary concern. In this study, rats—a standard model for mammalian toxicity—received glyphosate for 30 days, and some were also given vitamin E, a natural antioxidant present in many feedstuffs. Glyphosate damaged several organs, including the liver, lungs, kidneys, testes, and heart. Although the blood markers of oxidant load did not rise as expected, the animals’ antioxidant defences increased and the tissue damage itself was consistent with oxidative injury. Co-treatment with vitamin E strengthened antioxidant capacity and protected the organs from much of the damage. These findings suggest that vitamin E may help limit the harmful effects of long-term glyphosate exposure in animals and could serve as a simple, protective dietary supplement.
Results imply that gallic acid could serve as a protective or supportive therapy against hepatotoxicity resulting from glyphosate exposure, and imply that gallic acid could serve as a protective or supportive therapy against hepatotoxicity resulting from glyphosate exposure.
Mahsum Barçin, Mustafa Yılmaz, Eda Yıldızhan et al.· Revista Científica de la Fac...· 0 citations
This study provides the first demonstration that asiatic acid exerts robust systemic antioxidative, hepatoprotective, and neuroprotective effects against CPF-induced toxicity, highlighting AA’s therapeutic potential for mitigating organophosphate pesticide poisoning.
Özge Darakcı Saltık, H. Balcı, Figen Güzelgül et al.· Yüksek İhtisas Üniversitesi...· 0 citations
Safranal represents a promising bioactive countermeasure against organophosphate-induced systemic injury, however, further research is warranted to elucidate its precise transport mechanisms and potential limitations in crossing the blood-brain barrier.
Ahmet Büyükben, Ö. Hazman, Laçine Aksoy et al.· Animal Health Production and...· 0 citations
Industrial effluents/ wastewater is a primary source of hexavalent chromium (Cr(VI)) contamination in the environment. This pollutant, widely used in various industries, is highly toxic and persistent, making it one of the most significant global environmental concerns. Its hexavalent form is carcinogenic, genotox...
S. R. al-Saedi· Kerbala Journal of Veterinar...· 0 citations
Simple Summary Oxytetracycline is an antibiotic commonly used to treat bacterial diseases in farmed fish, but its use may also cause unwanted effects on fish health. Curcumin, a natural compound obtained from turmeric, has antioxidant and immune-supporting properties and may help reduce these adverse effects. This stud...
Meryem Sedef Doğru, Serpil Mişe Yonar, M. Dorucu et al.· Veterinary Sciences· 0 citations
Organophosphate pesticides are widely used in livestock production, yet their impact on the liver, particularly with repeated low-dose exposure in animals with underlying metabolic stress, remains poorly understood. We examined this using a goat model where treated animals received intermittent trichlorfon poisoning fo...
