TL;DR
Findings indicate that circ_0001495 may serve as a potential diagnostic/prognostic biomarker for BCa and promotes tumor progression by activating the miR-1184/MAPK signaling axis.
BACKGROUND Circular RNA (circRNA) has been recognized as critical regulator in cancer progression. However, the mechanisms of circ_0081069 in breast cancer (BC) remain understood. The study was designed to elucidate the pathological significance and mechanism of circ_0081069 in BC. MATERIAL AND METHODS The expression...
Circular RNAs (circRNAs) exhibit wide expression across human tissues and play pivotal roles in tumorigenesis and cancer progression. However, studies regarding the function and mechanism of circRNAs in lung adenocarcinoma (LUAD) are insufficient, it needs to be further explored. This investigation aimes to describe dy...
It is suggested that hsa_circ_0136682 drives breast cancer progression via the NCL/c-Myc axis.
In vivo, circPVT1 promoted tumor growth and lung metastasis, which were attenuated by co-expression of miR-195-5p, and molecular analysis of lung metastases confirmed the dysregulation of the circPVT1/miR-195-5p/PDK4 axis within metastatic lesions.
Background: Circular RNAs (circRNAs) are recognized as critical regulators of gastric cancer (GC) progression. Nevertheless, the biological function of circ_0088302 in gastric cancer and its epitranscriptomic regulatory mechanism remain unclear. Methods: The expression of circ_0088302 was analyzed based on plasma circR...
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