OEF18 is a membrane-anchored organellar Ca²⁺ sensor linking calcium signaling to jasmonate-mediated defense and stress acclimation

Peroxisome quality control is gated by a dynamic ATF6α–ABCD3 tether

The endoplasmic reticulum (ER) coordinates protein folding and lipid biosynthesis, while peroxisomes govern fatty-acid catabolism and redox balance. However, little is known about the mechanisms by which these organelles communicate. Here we show that activating transcription factor 6 (ATF6α), a cytoprotective ER-resid...

Arabidopsis BAG proteins regulate cellulose synthase stability

NTMC2T5 links lipid homeostasis to plastid differentiation

Chloroplast biogenesis requires extensive lipid remodeling to establish the internal membrane systems of developing plastids, yet how lipid homeostasis is coordinated during this process remains incompletely understood. Here, we identify a previously unrecognized, Archaeplastida-conserved family of SMP-domain proteins...

WHIRLY1 Interactome Profiling Reveals the Chloroplast Fate Correlation with Stromule-like Morphologies in Arabidopsis Leaves Under Dark and DBMIB Stress Conditions

The WHIRLY family comprises DNA/RNA-binding proteins localized to multiple subcellular compartments, including organelles and the nucleus. However, the subcellular distribution and functional roles of WHIRLY protein complexes are not fully characterized. In this study, a WHIRLY1 protein pulldown coupled with mass spect...

The Lateral Protein Cluster as a Key Component of Plant Cell Polarity

Cell polarity is an ancient organizing principle across kingdoms. As in animal epithelial cells, plant cells asymmetrically distribute proteins to establish functionally distinct membrane domains. In roots, radial polarity distinguishes inner and outer cell surfaces and supports directional nutrient transport, yet its...

Outer membrane proteins mediate unconventional secretion of Pseudomonas peroxidase through crosstalk between the Sec pathway and outer membrane vesicles

This study reveals the crosstalk between the Sec pathway and OMVs in the secretion of a non-canonical peroxidase, in which OM proteins, acting as the molecular tethers, mediate the stepwise secretion process and expands the understanding of non-classical protein secretion mechanisms and bacterial survival strategies.