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Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope Vaccine Against Influenza A H10N5 and H3N2 Strains Based on Hemagglutinin and Neuraminidase Proteins

Muhammad Zeeshan Shabbir Prem Kumar Muhammad Atiq ur Rehman Jeevan Kumar Umama Urooj Syeda Izza Batool Chandra Sourav Rumesa Ghazanfar Zainab Nagari Daniyal Hameed Abdul Wahid Ayesha Muhammad Daniyal Siddique
Jul 2026 · bioRxiv · 0 citations
Biology

TL;DR

The immunoinformatics based vaccine design and multi-layered computational validation of a 419-amino-acid multi-epitope subunit vaccine construct targeting conserved hemagglutinin (HA) and neuraminidase (NA) antigens identified through multiple sequence alignment of the avian H10N5 human reference strain sequences are reported.

DOI Semantic Scholar
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