TL;DR
A novel integration of capsaicin-mediated silver nanoparticles within a chitosan–alginate biopolymeric matrix is introduced, providing a multifunctional strategy that enhances both antimicrobial efficacy and wound regeneration compared to conventional systems.
A novel multifunctional wound dressing based on a composite of tannic acid-silver self-assembled nanoparticles (TA-AgNPs) and electrospun nanofiber membranes (NFMs) that combines excellent biocompatibility with mechanical properties demonstrates promising applications in chronic wound treatment.
Among the hydrogels, AG-AgNP-PE exhibited superior performance across all key properties, highlighting the synergistic effect of the nanomaterial combined with plant extracts within hydrogel cages and positioning it as a promising multifunctional wound dressing for rapid tissue regeneration and scar-free wound healing,...
Combining innovative processing with robust in vitro biological validation, this advanced formulation of copper oxide nanoparticles from Inula viscosa offers a viable technological alternative to conventional wound healing therapeutics.
The findings suggest that nanofiber wound dressings formulated with nanoscale materials represent a promising and effective alternative to conventional wound dressings, particularly for the therapeutic management of injuries associated with chemical, biological, radiological, and nuclear(CBRN) incidents.
Findings demonstrate that Aloe vera-mediated AgNPs can impart antibacterial functionality to electrospun PVA wound dressings, and careful optimization of the AgNPs concentration is essential to achieve an appropriate balance among antibacterial performance, cytocompatibility, and mechanical properties.
In vivo findings revealed accelerated wound closure, enhanced epidermal regeneration, and modulation of PDGFA, VEGFC, COL1A1, TIMP1, and MMP9 expression, and potential relevance to infection‑associated wound environments.
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