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Aug 2026

Temperature-Triggered Nanoscale Morphological Transitions in a Synthetic Intrinsically Disordered Protein.

Peptide self-assembly and liquid-liquid phase separation (LLPS), often mediated by intrinsically disordered regions (IDRs), are natural mechanisms that translate protein molecular features into complex nano- and mesoscale architectures. Although the thermodynamics and kinetics of these processes are well understood, sy...

Yulia Shmidov, Li-Xin Fan, Max R. Ney et al. · 0 citations
Sep 2026

Kinetic Pathway Selection in Supramolecular Polymerization via Transient Helical Inversion

Designing the organization of supramolecular systems with high-precision self-assembly along diverse pathways is a crucial strategy for optimizing functional properties. However, achieving such control remains a significant challenge in the field. Here, we report the selective pathway dynamics of platinum(II) terpyri...

Hyeon Min Han, Solme Ji, Soeun Jo et al. · 0 citations
Open access Aug 2026

Predictive Amphiphile Design Enables Control of Self-Assembled Nanoparticle-Cell Membrane Interactions.

Despite decades of development, the clinical translation of amphiphilic self-assembled nanoparticles remains limited by the lack of a predictive molecular design framework, owing to the complex, dynamic behavior of nanoparticles and cell membranes. Here, we introduce a building-block design strategy focused on amphiphi...

M. Nami, Tiffany Guitton-Spassky, Farhad Sharif et al. · 0 citations
Open access Sep 2026

Programming Intrinsic States of Solvent-Free Glycolipids through Molecular Architecture and Thermal History

Amphiphilic molecules enable the formation of diverse ordered structures across soft materials systems. The solution-phase self-assembly of glycolipids has been extensively investigated. However, the structural organization of these materials in the absence of solvent remains less systematically understood. It remains...

Won-Joo Kim, David E. Hogan, R. Maier et al. · 0 citations
Open access Aug 2026

Electrolyte-Controlled Self-Assembly of Water-Soluble Perylene Bisimides: A Kinetic and Stimulated Raman Study

Perylene bisimides (PBIs) are prime building blocks for functional supramolecular architectures, yet mapping their salt-induced self-assembly kinetics under physiological conditions remains challenging, due to rapid aggregation and overwhelming fluorescence. Here, we combine fluorescence stopped-flow kinetics and stimu...

M. Martinati, G. Batignani, Gaia De Maria et al. · 0 citations
Sep 2026

Supramolecular Janus Nanocylinders: Solvent-Induced Hydrogen-Bond Modulation Yields Structures under Thermodynamic Equilibrium

Janus nanocylinders (JNCs) are anisotropic, non-centrosymmetric colloids composed of two different faces, making them attractive for advanced functional materials. However, their nanometric dimensions and pronounced anisotropy complexify their preparation. Recently, a versatile supramolecular strategy has emerged tha...

Rihab Zguir, Ming-Sheng Ji, Irene Antignano et al. · 0 citations

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