A Pichia pastoris-based platform for large-scale production of functional recombinant human serum albumin with therapeutic efficacy

Lijiong Li Jing Lin Mengfa Cui Hai-Long Fu Zhi-Lin Wang

Jul 2026 · Bioprocess and biosystems engineering (Print) · Vol 49, pp. 2213 - 2223 · 0 citations · 36 references

Medicine

TL;DR

This study provides the first in vivo evidence confirming the therapeutic equivalence and dose-effect relationship of P. pastoris-derived rHSA compared with pHSA, supporting its potential as a viable clinical substitute for plasma-derived albumin.

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