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Ethical Considerations on Artificial Intelligence, Health and Health Care. All That Glisters Is Not Gold

Sep 2026 · European Journal of Clinical Investigation · Vol 56 · 0 citations · 70 references
Medicine

Abstract

Artificial intelligence (AI) is transforming global health care through innovations in deep learning, generative models and agentic AI systems. Traditional reductionist approaches to complex pathophysiological pathways fail to capture the true complexity of disease, motivating the adoption of network medicine (NM), which models biological systems as dynamic, interconnected networks. When combined with AI, NM enables integration of multiomic data and better characterizes disease mechanisms to guide precision therapies. Nevertheless, the rapid diffusion of AI in health care also raises profound ethical, regulatory and social challenges, since only a small fraction of AI tools have achieved routine clinical use, often due to limited generalizability, opaque algorithms and workflow incompatibility.

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