Pleiotropic genetic architecture linking schizophrenia and substance use disorders

S. Aranda D. Koller S. Papiol M. Artigas A. M. Pérez-Gutiérrez J. González-Peñas M. Budde P. Jácome-Ferrer C. Arango K. Adorjan E. Vilella G. Muntané L. Martorell M. Heilbronner M. Moltó O. Rivero A. Navarro-Flores J. Bobes M. O. Kohshour B. Crespo-Facorro D. Reich-Erkelenz A. Gonzalez-Pinto E. Schulte M. Arrojo G. Flórez F. Senner I. Anghelescu V. Arolt D. E. Dietrich A. Fallgatter C. Figge M. Jager F.-U. Lang G. Juckel C. Konrad J. Reimer E. Reininghaus M. SchmauB A. Schmitt C. Spitzer Wil

Sep 2026 · medRxiv · 0 citations

Medicine

TL;DR

Findings suggest that part of SCZ liability reflects genetic susceptibility to SUDs with potential implications for patient stratification and clinical management.

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